“…4 Similarly, the Biologics Price Competition and Innovation Act and attempts to support generic drug use have often been stymied by tactics such as patient-directed coupon codes to reduce substitution of generic drugs and slow uptake of biosimilars. 5,6 By contrast, intervening directly upon drug waste at multiple levels—both for manufacturers and oncology clinics—may ultimately be a more effective mechanism for lowering the global costs of cancer care.…”