2012
DOI: 10.1586/ern.11.194
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Association of chronic divalproex sodium use and brain atrophy in Alzheimer’s disease

Abstract: Divalproex sodium has been widely use for the treatment of bipolar disorder, behavioral control in schizophrenia, seizure and agitation in Alzheimer's disease. With the advent of other mood stabilizers and anticonvulsants, the use of divaplroex sodium has been slightly decreased; however, it has been a major mediation for the treatment of such medical conditions. Beyond symptomatic effects on such neuropsychiatric conditions, it has also been proposed to hold some neurotoxicity effects, including reversible br… Show more

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