Association of cortical morphology, white matter hyperintensity, and glymphatic function in frontotemporal dementia variants
Die Xiao,
Jianyu Li,
Zhanbing Ren
et al.
Abstract:INTRODUCTIONFrontotemporal dementia (FTD) can be phenotypically divided into behavioral variant FTD (bvFTD), nonfluent variant primary progressive aphasia (nfvPPA), and semantic variant PPA (svPPA). However, the neural underpinnings of this phenotypic heterogeneity remain elusive.METHODSCortical morphology, white matter hyperintensities (WMH), diffusion tensor image analysis along the perivascular space (DTI‐ALPS), and their interrelationships were assessed in subtypes of FTD. Neuroimaging‐transcriptional anal… Show more
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