Association of depression and epilepsy in Rwanda: A prospective longitudinal study

Sebera, Fidele; Dedeken, Peter; Garrez, Ieme; Umwiringirwa, Josiane; Leers, Tim; Ndacyayisenga, Jean-Pierre; Mutungirehe, Sylvestre; Ndayisenga, Arlene; Niyonzima, Odette; Umuhoza, Georgette; Teuwen, Dirk E.; Boon, Paul A.M.J.

doi:10.1016/j.yebeh.2022.108993

Cited by 6 publications

(3 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Epilepsy and depression are known to have a bidirectional relationship[ 31 ]. Depression, notably the most frequent psychiatric comorbidity among epilepsy patients, greatly diminishes the quality of life[ 32 ]. Previous studies revealed that in patients with epilepsy, a nearly 2-fold increase in the risk of developing depression was observed[ 31 ].…”

Section: Discussionmentioning

confidence: 99%

Bibliometric analysis of research in epilepsy and comorbid depression from 2014 to 2023

Chen,

He,

et al. 2024

World J Psychiatry

View full text Add to dashboard Cite

BACKGROUND Epilepsy and depression have complicated bidirectional relationships. Our study aimed to explore the field of epilepsy comorbid with depression in a bibliometric perspective from 2014-2023. AIM To improve our understanding of epilepsy and depression by evaluating the relationship between epilepsy and depression, bibliometric analyses were performed. METHODS Epilepsy and depression-related publications from the last decade were retrieved from the Web of Science Core Collection. We conducted bibliometric and visual analysis using VOSviewer and CiteSpace, examining authorships, countries, institutions, journals of publication, co-citations of references, connections between keywords, clusters of keywords, and keywords with citation bursts. RESULTS Over the past ten years, we collected 1045 research papers focusing on the field of epilepsy and comorbid depression. Publications on epilepsy and depression have shown a general upward trend over time, though with some fluctuations. The United States, with 287 articles, and the University of Melbourne, contributing 34 articles, were the top countries and institutions, respectively. In addition, in the field of epilepsy and depression, Professor Lee, who has published 30 articles, was the most contributing author. The hot topics pay attention to the quality of life in patients with epilepsy and depression. CONCLUSION We reported that quality of life and stigma in patients with epilepsy comorbid with depression are possible future hot topics and directions in the field of epilepsy and depression research.

show abstract

Section: Discussionmentioning

confidence: 99%

Bibliometric analysis of research in epilepsy and comorbid depression from 2014 to 2023

Chen,

He,

et al. 2024

World J Psychiatry

View full text Add to dashboard Cite

show abstract

“…There are presently elderly people with various mental health challenges, including trauma, the stigma associated with older age, abuse, neglect, a low public profile, and a lack of basic needs. 21 Although depression was revealed as a seriously disabling mental health issue in post-genocide Rwanda, [22][23][24][25][26] social bonds and connections with family members were proven to be protective factors against geriatric depression. [27][28][29] On the other hand, a lack of family bonds and family dysfunction were reported as potential risk factors for geriatric depression.…”

Section: Rationalementioning

confidence: 99%

Prevalence and Family Determinants of Geriatric Depression Among Elderly People in Elderly Support Groups in Rwanda

Nshimyumuremyi¹,

Muziki²,

Harerimana³

et al. 2023

PRBM

View full text Add to dashboard Cite

Background:The 1994 Tutsi genocide in Rwanda significantly impacted family structure, with many people growing old alone and lacking social bonds and connections with family members. However, little is known about the contribution of the family environment to geriatric depression which was highlighted by WHO as a psychological problem with a 10% to 20% prevalence rate among the elderly worldwide. This study aims to investigate geriatric depression and associated family determinants among the elderly in Rwanda.Methods: With a community-based cross-sectional study design, we assessed geriatric depression (GD), quality-of-life enjoyment and satisfaction (QLES), family support (FS), loneliness, neglect, and attitude toward grief in a convenience sample of 107 participants (M=72.32, SD=8.79) aged between 60 and 95 years who were recruited from three groups of elderly people supported by the NSINDAGIZA organization in Rwanda. SPSS (version 24) was used for statistical data analysis; differences across various sociodemographic variables were tested for significance by an independent t-test; the relationship between study variables was tested by Pearson correlation analysis; and multiple regression analysis was performed to model the contribution of independent variables to dependent variables. Results: A total of 64.5% of the elderly scored above the threshold of the normal range of geriatric depression (SDS>49), with higher symptoms in women than in men. Multiple regression analysis indicated that family support and quality-of-life enjoyment and satisfaction were contributors to geriatric depression in the participants. Conclusion: Geriatric depression was relatively common in our participants. It is associated with the quality of life and family support received. Hence, adequate family-based interventions are needed to improve the well-being of geriatric people in their respective families.

show abstract

“…The burden of depressive symptom among patients with epilepsy (PWE) is a worldwide problem with a range of 9-55% in developed countries, and the meta-analysis result shows 23.1% (18)(19)(20). Different studies conducted in Nigeria, Guinea, Kenya, and Rwanda revealed that the prevalence of depressive symptoms among PWE was found to be 85.5, 66, 16.5, and 14.2%, respectively (21)(22)(23)(24). According to a meta-analysis and systematic review carried out in seven sub-Saharan countries, the prevalence of depressive symptoms among patients with epilepsy was 32.71% (25).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and factors associated with depressive symptoms among patients with epilepsy in Ethiopia: a national-based systematic review and meta-analysis

Tadesse,

Tinsae,

Nakie

et al. 2024

Front. Neurol.

View full text Add to dashboard Cite

BackgroundDepression is a major public health problem and negatively affects the quality of life of patients with epilepsy. Despite multiple studies investigating the magnitude and predictors, the results have been inconsistent. Therefore, this study aimed to estimate the pooled prevalence and factors associated with depressive symptoms among patients with epilepsy in Ethiopia.MethodsThe primary articles were searched using databases like PubMed, Google Scholar, CINAHL, SCOPUS, EMBASE, and African Journal Online. A total of 10 primary articles that assessed the prevalence and factors associated with depressive symptoms among patients with epilepsy in Ethiopia were included. A Microsoft Excel spreadsheet was used to extract the data, which was then exported to Stata version 14 for further analysis. The statistical heterogeneity was evaluated using the I2 test. Due to heterogeneity, a random effect meta-analysis model was employed. Publication bias was checked through Egger’s weighted regression test and funnel plot.ResultsA total of 10 primary studies with 3,532 participants were included. The pooled prevalence of depressive symptoms among patients with epilepsy was found to be 41.69% (95% CI, 37.70, 45.68). The pooled prevalence of depressive symptoms was 48.61, 42.98, 40.68, 38.27, and 34.80% in Oromia, SNNPs, Amhara, Addis Ababa, and Tigray, respectively, based on a sub-group analysis per regional state. Perceived stigma (AOR = 3.30, 95% CI: 1.40, 7.80), seizure frequency (AOR = 3.81, 95% CI: 1.03, 14.09), and perceived stress (AOR = 4.6, 95% CI: 1.05, 20.06) were factors associated with depressive symptoms.ConclusionWe found that depressive symptoms affects at least four out of ten patients with epilepsy, indicating an immense burden. Depressive symptoms were extremely prevalent in those who had high levels of stigma, a monthly seizure frequency of once or more, and perceived stress. Therefore, physicians should take extra precautions when treating patients with epilepsy who have certain conditions.Systematic review registrationThis study was registered according to The International Prospective Register of Systemic Review (PROSPERO) with the registration ID (CRD42023484308).

show abstract

Association of depression and epilepsy in Rwanda: A prospective longitudinal study

Cited by 6 publications

References 54 publications

Bibliometric analysis of research in epilepsy and comorbid depression from 2014 to 2023

Bibliometric analysis of research in epilepsy and comorbid depression from 2014 to 2023

Prevalence and Family Determinants of Geriatric Depression Among Elderly People in Elderly Support Groups in Rwanda

Prevalence and factors associated with depressive symptoms among patients with epilepsy in Ethiopia: a national-based systematic review and meta-analysis

Contact Info

Product

Resources

About