Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China

Liu, Fushui; Fang, Ting; Zhou, Fanyuan; Zhao, Meimei; Chen, Mei; You, Jianyu; Jin, Yuli; Xie, Jinmei; Liu, Zhongyong

doi:10.1155/2018/3259431

Cited by 54 publications

(51 citation statements)

References 29 publications

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“…The 2 patient groups had significant higher levels of the included variables than the healthy control group. This is in line with previous research 13 showing more anxiety and depression in patients in pain than in healthy controls. Moreover, the occurrence of high anxiety, high depression, and high pain in the Spanish patients is higher than in the Norwegian sample.…”

Section: Strengths and Limitationssupporting

confidence: 94%

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Pain and Depression Are Associated With More Anxiety in ME/CFS: A Cross-Sectional Cohort Study Between Norway and Spain

Strand

Castro-Marrero

Helland

et al. 2020

Clinical Medicine Insights: Psychiatry

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Objectives: Lasting, unexplained and high levels of pain may cause anxiety in patients with chronic fatigue syndrome. The objectives of the current study were to test assumptions of the association between pain and anxiety in patients diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and to clarify the role of depression in this relationship. Methods: Data were collected from 664 participants (age 18-65 years) with 133 ME/CFS patients and 201 healthy controls from Norway and 330 CFS patients from Spain. Binary logistic regression model was applied to test relationships between the included variables in the samples. Results: Both pain and depression made significant direct contributions to the level of anxiety. The strongest risk for higher levels of anxiety was the combination of high levels of depression and high levels of pain in the overall sample (OR = 49.70; P < 0.001), not so much in the Spanish cohort (OR = 11.99; P < 0.0001) and most of all in the Norwegian cohort (OR = 88.21; P < 0.001) sample. Conclusions: It was the combination of high pain levels and high levels of depression that to the greatest extent increased the risk of anxiety in patients with CFS/ME. Whatever diagnostic criterion that is applied, anxiety and depression should be mandatory to assess in the clinical assessments performed for diagnosing the ME/CFS. Approaches addressing anxiety-related pain and treatment of depression should be warranted.

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Section: Strengths and Limitationssupporting

confidence: 94%

“…7,8 Mental health problems are common in patients with chronic pain disorders. [9][10][11][12] Anxiety and depression are more common in patients with neck pain than in healthy controls, 13 and are important predictors of pain and disability. There is a bidirectional relationship between pain and mental health problems.…”

Section: Introductionmentioning

confidence: 99%

Pain and Depression Are Associated With More Anxiety in ME/CFS: A Cross-Sectional Cohort Study Between Norway and Spain

Strand

Castro-Marrero

Helland

et al. 2020

Clinical Medicine Insights: Psychiatry

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“…The patients with temporomandibular disorders who have anxiety and depressive symptoms are more likely to develop migraine and primary headache 10. According to a systematic review, depressive symptoms and anxiety symptoms are associated with high morbidity neck pain 11…”

Section: Introductionmentioning

confidence: 99%

Association between severity of depressive symptoms and chronic knee pain in Korean adults aged over 50 years: a cross-sectional study using nationally representative data

Han

Lee

et al. 2019

BMJ Open

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ObjectivesTo identify the association between the presence and severity of depressive symptoms and those of chronic knee pain.DesignA retrospective cross-sectional study.ParticipantsWe used data from the sixth Korea National Health and Nutrition Examination Survey (KNHANES VI-2) performed in 2014. Overall, 7550 patients were included in the KNHANES VI-2.Outcome measuresParticipants were asked whether they had chronic knee pain, and each answer was either ‘yes’ or ‘no’. Patient Health Questionnaire-9 (PHQ-9) was used as a screening tool for depressive symptoms, and PHQ-9 scores of 10 or higher was classified as the depressed group. In total, 527 patients reported that they had pain in their knee, of whom 91 also had depressive symptoms.ResultsThe prevalence of chronic knee pain in the Korean population aged over 50 years was 19.8%. Multiple logistic regression was conducted after adjustment for sex, age, smoking, alcohol drinking, education level, household income, physical activity, sleep duration and comorbidity. The analysis revealed a significant association between depressive symptoms and chronic knee pain (adjusted OR=2.333, p<0.001). In contrast, the severity of depressive symptoms was linearly correlated with the intensity of chronic knee pain (p for trend <0.001). In participants with no chronic knee pain (Numerical Rating Scale; NRS=0) or mild chronic knee pain (NRS=1–4), the prevalence of moderate and severe depressive symptoms was 3.4% and 0.6%, respectively. However, in those with severe chronic knee pain (NRS=8–10), there was a higher prevalence of moderate and severe depressive symptoms (10.1% and 5.8%, respectively) (p<0.001).ConclusionsA strong association was observed between the presence and severity of depressive symptoms and the presence of chronic knee pain. The association became stronger with higher levels of depressive symptoms, indicating a positive correlation between depressive symptoms severity and chronic knee pain.

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“…In fact, the correlation between depression, anxiety, stress, and the cervical/cervicobrachial area is well described in the literature. [23][24][25][26][27][28][29][30] Furthermore, it has been shown that this correlation is present in all ages. 25,27 The purpose of this study was analyzing retrospectively the data obtained from the psychometric test depression Anxiety Stress Scale 21 items (DASS-21) 31 in the NPPO and NPPO-CB groups.…”

Section: Introductionmentioning

confidence: 89%

REAC Neuromodulation Treatments in Depression, Anxiety and Stress. A Comparative Retrospective Study

Barcessat¹,

Bittencourt²,

Gonçalves³

et al. 2020

PRBM

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Introduction The purpose of this retrospective study was to compare the effects of two different modalities of administration of the neuro psycho physical optimization (NPPO) neuromodulation treatment, applied with radio electric asymmetric conveyer (REAC) biotechnology devices. Both the modalities are aimed at improving the strategies to deal with and optimize the allostatic response to environmental stressors and exposome. This allows to reduce the dysfunctional adaptive behavior patterns, which underlie many neuropsychological symptoms and pathologies, and to improve the symptoms of depression, anxiety and stress. Materials and Methods From a population of subjects experiencing at least two of the three symptoms depression, anxiety and stress, the selection of pre and post-treatment Depression, Anxiety, Stress 21 items scale (DASS 21) data was made proceeding with a reverse chronological recruitment mechanism, until reaching 150 subjects for each of the 2 groups. The first group was treated with the neuro psycho physical optimization treatment (NPPO), which is the punctiform modality of administration on the auricle pavilion, and the second group was treated with the neuro psycho physical optimization treatment, which is the area modality of administration applied by the planar probe on the cervicobrachial area (NPPO-CB). Results The Wilcoxon signs test confirmed the differences in scores in pre and post-treatment DASS-21. The comparison between the two groups data and the comparison across groups data showed that NPPO and NPPO-CB have the same efficacy in reducing the symptoms of depression, anxiety and stress, after a single treatment cycle. Statistical significance was set at p <0.05. Discussion This is the first efficacy descriptive comparison between the two different modalities of administration of the NPPO treatment, as different options for the same clinical indication.

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Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China

Cited by 54 publications

References 29 publications

Pain and Depression Are Associated With More Anxiety in ME/CFS: A Cross-Sectional Cohort Study Between Norway and Spain

Pain and Depression Are Associated With More Anxiety in ME/CFS: A Cross-Sectional Cohort Study Between Norway and Spain

Association between severity of depressive symptoms and chronic knee pain in Korean adults aged over 50 years: a cross-sectional study using nationally representative data

REAC Neuromodulation Treatments in Depression, Anxiety and Stress. A Comparative Retrospective Study

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