Association of dietary intake and cervical cancer: a prevention strategy

Abstract

Introduction Cervical cancer is one of lethal cancers in women. As a global concern, identifying important factors of cancer is a useful strategy for prevention. Due to the role of diet/nutrition factors for cancer, the purpose of our study was to determine the impact of 150 nutrition/vitamin factors and 50 non-nutritional factor in cervical cancer and phase. Methods Population samples of 2088 healthy subjects and patients with cervical cancer were investigated. 200 factors such as vitamin E, B1, B6, fruits, HPV, and age were gathered. Deep learning, Decision tree, and correlation matrix were used for modeling and identifying important factors. SPSS 26, R4.0.3, and Rapid miner were utilized for implementation. Results Our findings indicated that zinc, Iron, Niacin, Potassium, Phosphorous, and Cooper have a beneficial impact in reducing the risk of cervical cancer and progression of phase in Iranian women, as well as Salt, snacks and milk Were identified as high-risk food factors (P value < 0.05 and coefficient correlation > 0.6). Also, alcohol, and sex patient with two groups, HPV positive have an impact on cervical cancer incidence. Phosphorus and selenium in the Micronutrients category (R2 = 0.85, AUC = 0.993) and polyunsaturated fatty acid and salt in the Macronutrients category and other categories of nutrients were identified as the most effective factors in cervical cancer using deep learning (R2 = 0.93, AUC = 0.999). Conclusions A diet and rich nutrition can be helpful for the prevention of cervix cancer and may reduce the risk of disease. Additional research is necessary for different countries.

Advancements in the Management of Cervical Intraepithelial Neoplasia: A Comprehensive Review

“…Nutritional and lifestyle interventions are pivotal in managing CIN. Research indicates that dietary factors can influence CIN risk, with specific nutrients such as carotenoids, folate, vitamins C and E, and other B vitamins potentially affecting CIN development and progression [ 53 , 54 ]. Studies have demonstrated that a low intake of fruits and vegetables correlates with an elevated risk of CIN.…”

“…Studies have demonstrated that a low intake of fruits and vegetables correlates with an elevated risk of CIN. In contrast, higher serum levels of specific nutrients like carotenoids and gamma-tocopherol are associated with a decreased risk of high-grade CIN [ 53 , 54 ]. Additionally, lifestyle modifications encompassing attention to diet, social habits, sexual behavior, and vaccination can significantly contribute to cervical cancer prevention and CIN management [ 53 ].…”

“…In contrast, higher serum levels of specific nutrients like carotenoids and gamma-tocopherol are associated with a decreased risk of high-grade CIN [ 53 , 54 ]. Additionally, lifestyle modifications encompassing attention to diet, social habits, sexual behavior, and vaccination can significantly contribute to cervical cancer prevention and CIN management [ 53 ]. Factors such as alcohol consumption and smoking have been linked to increased risks, while maintaining a diet abundant in fruits, vegetables, and nutrients like zinc, iron, niacin, potassium, and phosphorus may potentially diminish the risk of cervical cancer and CIN progression [ 53 ].…”

“…Additionally, lifestyle modifications encompassing attention to diet, social habits, sexual behavior, and vaccination can significantly contribute to cervical cancer prevention and CIN management [ 53 ]. Factors such as alcohol consumption and smoking have been linked to increased risks, while maintaining a diet abundant in fruits, vegetables, and nutrients like zinc, iron, niacin, potassium, and phosphorus may potentially diminish the risk of cervical cancer and CIN progression [ 53 ]. Lifestyle choices, including steering clear of high-risk diets, maintaining a healthy diet, and undergoing HPV vaccination, constitute crucial components of a comprehensive approach to CIN management.…”

“…Lifestyle choices, including steering clear of high-risk diets, maintaining a healthy diet, and undergoing HPV vaccination, constitute crucial components of a comprehensive approach to CIN management. The integration of nutritional considerations and lifestyle modifications into CIN management is imperative for mitigating the risk of cervical cancer progression and enhancing patient outcomes [ 53 , 54 ].…”