Association of DNA Polymorphisms Within the CYP11B2/CYP11B1 Locus and Postoperative Hypertension Risk in the Patients With Aldosterone-producing Adenomas

Factors Affecting Complete Hypertension Cure after Adrenalectomy for Aldosterone-Producing Adenoma: Outcomes in a Large Series

“…In line with previous studies [7,8,9,21], in our group of patients duration of hypertension can be considered as an independent factor: longer hypertension duration gives a lower recovery percentage. In our opinion, this is not only due to the long-term high blood pressure induced detrimental and irreversible effects on the cardiovascular system, but also the longer duration of hypertension means a longer duration of aldosterone excess.…”

Blood pressure and medication changes following adrenalectomy for unilateral primary aldosteronism

“…Previous studies that used AVS selectively have reported no difference in outcome between patients Outcome of surgery in primary aldosteronism undergoing surgery on the grounds of a typical adenoma on CT-scan or on the grounds of lateralized AVS performed in patients without a typical adenoma on CT-scan [14,16,22,33]. Moreover, among the 19 studies reported in our literature review, the six that used AVS systematically did not have a better pooled cure rate (39%) [18][19][20]29,30,32] than the 13 that used AVS selectively (42%) [12,14,16,17,21,[23][24][25][26][27][28]31,33]. Finally, among patients with unilateral primary aldosteronism systematically diagnosed by AVS, those with the highest lateralization index did not have a higher rate of hypertension cure [29].…”

Prevalence and Characterization of Somatic Mutations in Chinese Aldosterone-Producing Adenoma Patients

“…APA was diagnosed following previously described procedures. 21 Written informed consent was obtained from all patients included in this study. This study was approved by the Protection of Human Subjects Committee of the Chinese PLA General Hospital.…”