Association of elective cesarean delivery with metabolic measures in childhood: A prospective cohort study in China

Zhou, Yubo; Li, H.-T.; Si, Keyi; Zhang, Y.-L.; Wang, L.-L.; Liu, J.-M.

doi:10.1016/j.numecd.2019.04.007

Cited by 10 publications

(24 citation statements)

References 39 publications

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“…After reviewing the titles and abstracts, 43 relevant studies were obtained. After reading the full text, a total of 9 studies met the inclusion criteria and were used for final meta-analysis (16)(17)(18)(20)(21)(22)(23)(24)(25) (Figure 1).…”

Section: Characteristics Of the Selected Studiesmentioning

confidence: 99%

Effect of Elective Cesarean Section on Children's Obesity From Birth to Adolescence: A Systematic Review and Meta-Analysis

Zhang

Qin

et al. 2022

Front. Pediatr.

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BackgroundElective cesarean section (ECS) is the most common reason for the increasing cesarean section rate worldwide, and it is reported to be related to adverse short-term and long-term outcomes in both mothers and infants. Findings on the association between ECS and overweight and obesity in children are controversial in recent studies. Therefore, we conducted a systematic review and meta-analysis to examine the effect of ECS on offspring's overweight and obesity.MethodsPubMed, Science Direct, Web of Science, CNKI (China National Knowledge Infrastructure), Wanfang Database (in Chinese), and China Biology Medicine disc databases were searched using different combinations of three groups of keywords: “elective cesarean section,” “overweight/obesity,” and “children.” Nine cohort studies and 11 independent risk estimates were finally identified.ResultsWe have observed significant association between ECS and children's obesity, the total pooled risk ratio (RR) being 1.10 (95% CI: 1.01–1.18; I2 = 32.4%). In subgroup analysis, ECS was found to be associated with the occurrence of obesity in preschoolers (RR = 1.12, 95% CI: 1.02–1.22; I2 = 16.8%). Furthermore, it revealed that ECS was related with the high risk of children's obesity where the rate of ECS exceeded 10%. No significant association was observed between ECS and children's overweight, and the RR was 1.12 (95% CI: 0.94–1.30; I2 = 55.6%).ConclusionsOverall, it indicated that children born via ECS had an increased risk of later-life obesity. Given the global increase in childhood obesity, our findings would provide evidence-based reference for early life intervention on children's obesity.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021267211, identifier: CRD42021267211.

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Section: Characteristics Of the Selected Studiesmentioning

confidence: 99%

Effect of Elective Cesarean Section on Children's Obesity From Birth to Adolescence: A Systematic Review and Meta-Analysis

Zhang

Qin

et al. 2022

Front. Pediatr.

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“…In another study that included only 21,051 men in Denmark, it was found out that CS increases the risk for obesity 1.35 times in young male adults 13 . A cohort study reported that CS was associated with central obesity and hypertension but not with metabolic syndrome in early and middle childhood 14 . The BMI and waist circumference values were higher in the CS group in our study, but there was no statistically significant difference between the two groups in terms of systolic and diastolic blood pressure.…”

Section: Discussionmentioning

confidence: 99%

Sezaryen ile Doğmuş Genç Erişkinlerin Kardiyovasküler Sistem Özellikleri

Akşıt¹,

Gazı²,

Kırılmaz³

et al. 2020

Namık Kemal Tıp Dergisi

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Aim: Currently, the prevalence of caesarean section (CS) has been increasing at an alarming rate across the world. In parallel with the increasing rate of CS, it is reported that there is an increasing prevalence of obesity, autoimmune and allergic diseases. The purpose of the present study is to analyse whether the cardiovascular system characteristics of young adults born by CS are different from those of young adults born by vaginal delivery (VD). Materials and Methods: A total of 112 participants were included in the study (40 CS group vs 82 VD ie control group). Transthoracic echocardiography and carotid Doppler ultrasonography were performed to the participants. In addition, participants were evaluated with a 24-hour ECG recording. Results: Tricuspid E wave, tricuspid A wave and tricuspid E/A ratio were lower in the CS group compared with the control group (57.6±8.6 vs. 72.4±10.3, p<0.001; 46.7±8.8 vs. 50.6±8.9, p=0.04; 1.2±0.14 vs 1.45±0.88, p<0.001). Epicardial fat tissue thickness were higher in the CS group compared with the control group (4.8±1.3 vs. 3.1±0.8, p<0.001). Conclusion: The results of this study show that cardiovascular system features of the young adults born by CS are different from those born by VD. Further follow-up studies are needed to understand whether these findings will subsequently result in cardiovascular diseases.

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“…CDMR can have an additional influence on the future body weight and development of children. In a recent study by Zhou et al, elective CD was found to have an association with central obesity and hypertension in children aged 4 to 7 years old [ 52 ]. In a study by Li et al, CDMR was found to be correlated with the lowest probability of developing psychopathological problems in children of preschool age, followed by spontaneous vaginal delivery and associated vaginal delivery [ 53 ].…”

Section: Discussionmentioning

confidence: 99%

Does Obesity Influence Women’s Decision Making about the Mode of Delivery?

Różańska-Walędziak

2022

JCM

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Introduction: The ratio of cesarean deliveries (CDs) has been increasing worldwide, with a growing problem of cesarean delivery on maternal request (CDMR) and an alarmingly increasing rate of CD in the private sector. There are numerous factors influencing women’s preferences for the mode of delivery and their opinion about shared decision making (SDM). Material and method: The study was designed as an online survey, filled in by 1040 women. The questionnaire included questions about women’s preferences for the mode of delivery, their opinions about CDMR and the process of decision making regarding the mode of delivery. Results: There were no statistically significant differences found between women with a BMI ≤ 25 kg/m2 and >25 kg/m2, nor with a BMI ≤ 30 kg/m2 and >30 kg/m2, on the subject of the preferred method of delivery, and the opinion regarding SDM and CDMR without medical indications. More than 85% of women in all groups, who preferred CD as the mode of delivery, wanted to have CDMR. Conclusion: We have not found obesity and overweight to be a factor influencing women’s preferred mode of delivery, their opinion about SDM and their preference for CDMR without medical indications. However, the sample size of women with morbid obesity with a BMI ≥ 35 kg/m2 was too small for the results to be considered significant in this group, and it will therefore be subject to further studies.

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Association of elective cesarean delivery with metabolic measures in childhood: A prospective cohort study in China

Cited by 10 publications

References 39 publications

Effect of Elective Cesarean Section on Children's Obesity From Birth to Adolescence: A Systematic Review and Meta-Analysis

Effect of Elective Cesarean Section on Children's Obesity From Birth to Adolescence: A Systematic Review and Meta-Analysis

Sezaryen ile Doğmuş Genç Erişkinlerin Kardiyovasküler Sistem Özellikleri

Does Obesity Influence Women’s Decision Making about the Mode of Delivery?

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