Association of Electronic Cigarette Vaping and Cigarette Smoking With Decreased Random Flap Viability in Rats

Abstract

IMPORTANCESmoking is a known risk to wound healing, but whether electronic cigarettes present the same risk remains unknown.OBJECTIVE To evaluate the rate of flap necrosis in the e-cigarette vapor-exposed group and the unexposed control and to detect a difference in the rate of flap necrosis between the traditional cigarette smoke-exposed group and the unexposed control.

Oral erosions associated with surreptitious marijuana vaping in an adolescent boy

“…Increasing evidence indicates that vaping also harms skin. In a study comparing the effects of cigarette smoking and e‐cigarette use on wound healing, vaping was just as likely to cause skin flap necrosis as smoking . Furthermore, battery malfunction in vaping devices or e‐cigarettes can cause thermal burn injuries to the skin.…”

“…In a study comparing the effects of cigarette smoking and e-cigarette use on wound healing, vaping was just as likely to cause skin flap necrosis as smoking. 9 Furthermore, battery malfunction in vaping devices or e-cigarettes can cause thermal burn injuries to the skin. Reported injuries include superficial, partial, or full-thickness burn injuries to the legs after spontaneous combustion of the vaping device in the user's pocket 10 and facial burns and trauma after combustion during use.…”

Are electronic cigarettes and vaping effective tools for smoking cessation? Limited evidence on surgical outcomes: a narrative review

“…There is a severe paucity of data on the impact of e-cigarette use on surgical outcomes and wound healing. One such study examined skin flap survival using a rat model exposed to e-cigarettes in a smoking chamber, where nicotine containing e-cigarettes were found to negatively impact skin flap survival and tissue perfusion (63,64). When compared to controls, significantly higher rates of dorsal skin flap necrosis were found in rats exposed to nicotine containing e-cigarettes and tobacco cigarettes (63,64).…”

“…One such study examined skin flap survival using a rat model exposed to e-cigarettes in a smoking chamber, where nicotine containing e-cigarettes were found to negatively impact skin flap survival and tissue perfusion (63,64). When compared to controls, significantly higher rates of dorsal skin flap necrosis were found in rats exposed to nicotine containing e-cigarettes and tobacco cigarettes (63,64). Of note, similar rates of dorsal skin flap toxicity and necrosis were found between e-cigarette and tobacco smoke exposed groups, illustrating the deleterious effects of nicotine exposure on wound healing (63,64).…”

Skin Resurfacing

“…This may preclude ablative resurfacing in some situations, and resurfacing should only be pursued with caution by an experienced physician. Most physicians performing full-field ablative laser resurfacing require smoking cessation, to optimize wound healing, prior to laser treatment [21,22].…”