Association of eosinophilic inflammation with esophageal food impaction in adults

Desai, Tusar K.; Stecevic, Veslav; Chang, Chung‐Ho; Goldstein, Neal S.; Badizadegan, Kamran; Furuta, Glenn T.

doi:10.1016/s0016-5107(05)00313-5

Cited by 375 publications

(269 citation statements)

References 24 publications

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“…[18,19] After these initial findings and the work that followed, it became evident that EoE should be treated. [8,9,18,19] Due to the rareness of purely observational studies, our understanding of the natural history of EoE remains limited.…”

Section: Discussionmentioning

confidence: 99%

“…[2][3][4][5][6] Adult EoE patients primarily suffer from dysphagia, often culminating in food impaction necessitating endoscopic bolus removal. [7][8][9] The endoscopic presentation of EoE is quite variable. Recently, the endoscopic features of EoE have been graded by Hirano et al [10] For the purposes of this study, characteristic features of EoE were classified into two categories, the inflammatory and the fibrotic group of EoE features.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Delay in Diagnosis of Eosinophilic Esophagitis Increases Risk for Stricture Formation in a Time-Dependent Manner

Schoepfer

Safroneeva

Bussmann³

et al. 2013

Gastroenterology

632

517

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Delay in Diagnosis of Eosinophilic Esophagitis Increases Risk for Stricture Formation in a Time-Dependent Manner

Schoepfer

Safroneeva

Bussmann³

et al. 2013

Gastroenterology

632

517

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“…In the adult population, EoE primarily affects middle-aged White males. The typical presentation in this age group is one of recurrent solid food dysphagia or food impaction [Desai et al 2005]. EoE has been documented in association with allergic conditions such as asthma, eczema, food allergies, and seasonal aero-allergens.…”

Section: Background and Aimsmentioning

confidence: 99%

Routine screening for eosinophilic esophagitis in patients presenting with dysphagia

Ricker

McNear

Cassidy

et al. 2010

Therap Adv Gastroenterol

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Abstract:Background: Eosinophilic esophagitis (EoE) is a clinicopathologic disorder first described in 1978 which has gained significant recognition over the past 10 years. Numerous prevalence studies have been performed around the globe, both in pediatric and adult populations documenting a prevalence between 0.002% and 6.5%. The aim of this study is to assess the utility of routinely screening for EoE in patients with dysphagia. Methods: A prospective, observational study in which adult patients with a complaint of esophageal dysphagia were enrolled. Results: Of the 135 patients enrolled, 122 completed the study; 100 patients had nonobstructive dysphagia, while 22 patients had a luminal finding which could explain their dysphagia. The prevalence of EoE in the nonobstructive dysphagia group was 22% (95% CI: 13.930.1%); 32.7% of male patients with nonobstructive dysphagia were found to have EoE compared with 8.9% of females (p ¼ 0.004). The mean age of nonobstructive patients found to have EoE was 37.8 years. White patients with nonobstructive dysphagia were found to have a 25.9% prevalence of EoE, compared with 0% of African Americans, 0% of Asians, and 14.3% of Hispanics. When comparing Whites with non-Whites, the prevalence of EoE was noted to be 25.9% versus 5.3%, respectively (p ¼ 0.050). Conclusions: EoE is a common cause of nonobstructive dysphagia. We believe that the high prevalence of EoE in patients with nonobstructive dysphagia supports the practice of routine biopsies to screen for the presence of abnormally high numbers of eosinophils in this subgroup.

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“…[1,3] It is well known now that EE is a strong predictor of multiple esophageal food bolus obstructions (odds ratio 3.5; 95% CI, 1.8-7.0). [1,3,20] The combination of our patient's presumed EE and the hydrogel properties of chia seeds literally became a "recipe" for disaster. With the increasing popularity of chia seeds, patients with any history of underlying esophageal pathology should be cautioned about their use, especially in their dry form.…”

Section: Discussionmentioning

confidence: 99%

Watch it grow: Esophageal impaction with chia seeds

Simmelink

Rawl

Browne

et al. 2017

CRIM

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Esophageal obstructions are a medical emergency, due to inability to control secretions and risk of perforation. Epidemiology of esophageal foreign-body impaction has evolved to include increasing incidence of non-meat food causes as well as increasing underlying prevalence of pathologies including eosinophilic esophagitis. Chia seeds, a staple known for health benefits, have an uncanny ability to absorb large quantities of water leading to a hydrated gel-like substance which can cause an obstruction. We report the first case of chia seed impaction in a patient with likely eosinophilic esophagitis.

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Association of eosinophilic inflammation with esophageal food impaction in adults

Cited by 375 publications

References 24 publications

Delay in Diagnosis of Eosinophilic Esophagitis Increases Risk for Stricture Formation in a Time-Dependent Manner

Delay in Diagnosis of Eosinophilic Esophagitis Increases Risk for Stricture Formation in a Time-Dependent Manner

Routine screening for eosinophilic esophagitis in patients presenting with dysphagia

Watch it grow: Esophageal impaction with chia seeds

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