Association of epicardial fat thickness assessed by echocardiography with the severity of coronary artery disease

Rostamzadeh, Alireza; Khademvatani, Kamal; Mohammadzadeh, Mir Hossein Seyed; Ashori, Shahrzad; Poorrafsanjani, M. Hajahmadi; Rahimi, Behzad; Ghadrdoost, Behshid

doi:10.34172/jcvtr.2020.19

Cited by 4 publications

(3 citation statements)

References 20 publications

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“…17 Some studies analyzed EAT linear thickness on transthoracic echocardiography, CT oMRI. 18,19 EAT 3D volume quantification on cardiac CT is considered the most accurate measurement with the most literature describing its value. 17 Nevertheless, EAT volume as measure of cardiac inflammation has some major limitations.…”

Section: The Role Of Epicardial Adipose Tissuementioning

confidence: 99%

Evaluation of pericoronary adipose tissue attenuation on CT

Fari

Harst

et al. 2023

The British Journal of Radiology

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Pericoronary adipose tissue(PCAT) is the fat deposit surrounding coronary arteries. Although PCATis part of the largerepicardial adipose tissue (EAT) depot, it has different pathophysiological features and roles in the atherosclerosis process.While EAT evaluation has been studied for years, PCAT evaluationis a relatively new concept. PCAT, especially the mean attenuationderived from CT imagesmay be used to evaluate the inflammatory status of coronary arteries non-invasively.The most commonly used measure, PCATMA, is the mean attenuation of adipose tissue of 3 mm thickness around the proximal RCA with a length of 40 mm. PCATMAcan be analyzed on a per-lesion, per-vessel or per-patient basis. Apart from PCATMA, other measures for PCAT have been studied, such asthickness, and volume.Studies have shown associations between PCATMAandanatomicaland functional severity of CAD. PCATMA is associated withplaque components and high-risk plaque features,and can discriminate patients with flow obstructing stenosis and myocardial infarction.Whether PCATMAhas value on an individual patient basis remains to be determined. Furthermore, CT imagingsettings, such as kV levelsand clinical factors such as age and sex affect PCATMAmeasurements, whichcomplicate implementation in clinical practice. For PCATMAto be widely implemented, a standardized methodologyis needed. This review gives an overview of reported PCATmethodologies used in current literature and the potential use cases in clinical practice.

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Section: The Role Of Epicardial Adipose Tissuementioning

confidence: 99%

Evaluation of pericoronary adipose tissue attenuation on CT

Fari

Harst

et al. 2023

The British Journal of Radiology

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“…выявлена значимая взаимосвязь эпикардиального ожирения с развитием дислипидемии и мультифокального субклинического атеросклероза [14]. Толщина ЭЖТ, измеренная методом ЭхоКГ, была значительно выше у пациентов с ИБС, чем у пациентов в группе контроля и коррелировала с тяжестью поражения коронарных сосудов по шкале SYNTAX [15]. Прослеживается также связь ЭЖТ с типом атеросклеротической бляшки.…”

Section: передовая статья обзоры литературыunclassified

Role of epicardial adipose tissue in the development of cardiovascular diseases

et al. 2022

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Epicardial adipose tissue (EAT) has unique properties due to its special anatomical structure, thermoregulation, and metabolic activity. Dysregulated EAT provokes the synthesis of pro-inflammatory cytokines, disorders in the metabolism of fats and glucose, as well as contributes to fatty degeneration of the myocardium and heart failure development. EAT may serve as a risk factor and biomarker for cardiovascular diseases, and is also a potential therapeutic target. The purpose of this review was to highlight current research data on EAT, secreted adipokines, their effect on target tissue metabolism, and to systematize the relationship between EAT and cardiovascular diseases. In particular, its function, role in heart failure, atrial fibrillation, as well as the prognostic value of various microRNAs determined in EAT are highlighted.

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“…При измерениях всегда следует использовать анатомические ориентиры: положение межжелудочковой перегородки и кольца аорты. Спорный момент заключается в том, какое время сердечного цикла является наиболее подходящим для измерения толщины EAT: некоторые исследователи рекомендуют проводить измерение во время систолы, чтобы предотвратить возможную деформацию при сжатии жировой ткани во время диастолы, другие -в диастоле [40,41]. Толщина EAT, определенная при помощи УЗИ методов, показала хорошую корреляцию со значениями, полученными по данным МРТ (r=0,91, p=0,001) [41].…”

Section: передовая статья обзоры литературыunclassified

Obesity as a risk factor for cardiovascular disease: focus on ultrasound

Цыганков¹,

Поликутина

2021

Russ J Cardiol

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For many decades, obesity has been one of the main risk factors for cardiovascular disease. Despite medical advances, the obesity increases contribution to morbidity and mortality from cardiovascular diseases. Numerous anthropometric criteria for obesity are well-studied, simple and inexpensive tools for diagnosing overweight in the population. However, their accuracy is comparatively low. In particular, it is impossible to determine body composition based on these criteria, which is a key point in cardiovascular risk stratification. Despite the relatively short period of ultrasound practice for obesity diagnosis, convincing evidence has already been obtained of their high accuracy and effectiveness in predicting the risk of cardiovascular disease. Given the continuous improvement of ultrasound equipment, the studied criteria should be implemented in routine clinical and research practice. This literature review describes the central parameters used in the ultrasound diagnosis of obesity, their contribution to both conventional risk factors and cardiovascular diseases itself.

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Association of epicardial fat thickness assessed by echocardiography with the severity of coronary artery disease

Cited by 4 publications

References 20 publications

Evaluation of pericoronary adipose tissue attenuation on CT

Evaluation of pericoronary adipose tissue attenuation on CT

Role of epicardial adipose tissue in the development of cardiovascular diseases

Obesity as a risk factor for cardiovascular disease: focus on ultrasound

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