Association of estrogen receptor 1 intron 1 C/T polymorphism in Korean vitiligo patients

Association of vitiligo with HLA‐A2: a meta‐analysis

“…Besides the association of vitiligo with CTLA‐4, vitiligo has been reported to be associated with several other genes (non‐HLA), such as the oestrogen receptor 1 gene, 46 the angiotensin‐converting enzyme gene, 47 the catalase gene, 48 the catechol‐ O ‐methyltransferase gene 49 and the lymphoid protein tyrosine phosphatase gene 50 . These observations, together with our findings in this study, provide evidence and support that the onset of vitiligo is complex and could be affected by multiple genes 1 .…”

Association of glutathione S-transferase gene polymorphisms (GSTM1 and GSTT1) of vitiligo in Korean population

“…The genetic background underlying vitiligo susceptibility has been proposed in various studies (Spritz, 2006;Zhang et al, 2005). Several candidate genes have been proposed for vitiligo susceptibility, including catalase (CAT) gene (Casp et al, 2002;Park et al, 2006), angiotensin-converting enzyme (ACE) gene (Jin et al, 2004a), estrogen receptor 1 (ESR1) gene (Jin et al, 2004b) and cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) gene (Blomhoff et al, 2005).…”

The Arg160Trp Allele of Melanocortin‐1 Receptor Gene Might Protect Against Vitiligo†

“…These findings all confirm the well‐known dominant autoimmune background of the disease. However, worldwide studies on divergent ethnic groups have revealed a number of other candidate genes in disease susceptibility that are not directly involved in immunologic functions (1,15–19). Genes related to human pigmentation have been studied to date only in Korean vitiligo patients (4) but not in Caucasians.…”