2010
DOI: 10.21608/besps.2010.36302
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Association of Estrogen Receptor Α Pvu Ii and Xbai Gene Polymorphisms With Breast Cancer Risk; Relation to the Age of Menarche and Menopause

Abstract: The association of estrogen receptor-α (ER-α) genetic polymorphisms with the risk of breast cancer attracts much attention because ER functions as a hormone-dependent transcriptional regulator, which in turn, plays a significant role in the development of breast cancer. This study was conducted to find if there is an association between genetic polymorphisms in the ER-α gene and breast cancer in Egyptian females and its relation to the age of menarche and menopause. A total of 50 breast cancer Egyptian women a… Show more

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