The importance of a person’s belief in their own academic abilities cannot be overstated when it comes to pursuing further education and selecting a career aligned with their studies. This research investigates the influence of family dynamics and background, behavior and values, school experiences and out-of-school experiences on academic self-efficacy (ASE). The study also examines how sub-variables of behaviors and values mediate the development of self-efficacy. The research employs a quantitative cross-sectional survey with a convenience sample of 350 intermediate students from various academic domains. The data analyzed using Smart PLS 4 software, revealed that students’ behaviors and values, as well as their out-of-school experiences have a significant impact on the development of self-efficacy. All variables related to behaviors and values show a significant positive impact, except for decision-making skills, which have no significant effect. However, the indirect influence of technology is also noticed. On the other hand, most background factors and school experiences have no direct influence on ASE. This study offers valuable insights into the multifaceted factors that play a crucial role in family education, teacher education, and career counseling. Additionally, it provides a foundation for future research in this area and contributes to the understanding of adolescents; self-efficacy in academic domains.