Association of Human Milk Feedings With a Reduction in Retinopathy of Prematurity Among Very Low Birthweight Infants

Hylander, Mary Ann; Strobino, Donna M.; Pezzullo, John C.; Dhanireddy, Ramasubbareddy

doi:10.1038/sj.jp.7210548

Cited by 167 publications

(120 citation statements)

References 31 publications

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“…[4][5][6][7][8][9][10][11][12][13][14] Fortification of human milk with extra calories, protein, minerals and vitamins is required and produces significantly improved growth in comparison with unfortified milk. 30 Accurate human milk nutrient information is required as a result to manage human milk feeding for the VLBW infant.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5][6][7][8] Human milk is superior to all other forms of nutrition available for preterm infants and confers distinct health advantages to the preterm infant, particular with a reduction in necrotizing enterocolitis and sepsis. [4][5][6][7][8][9][10][11][12][13][14][15] However, human milk exhibits high variability in nutrient content between mothers, over the time course of lactation and even throughout the day. [16][17][18] This variability has the potential to introduce problems to the premature infant that is exclusively fed expressed human milk.…”

Section: Introductionmentioning

confidence: 99%

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Human milk macronutrient analysis using point-of-care near-infrared spectrophotometry

Sauer

Kim

2010

J Perinatol

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Objective: To demonstrate that the real-time nutritional analysis of human milk carbohydrate, fat and protein with near-infrared (NIR) spectrophotometric methods is accurate.Study Design: A prospective study of the measurement of the macronutrient content of human milk. Milk was first analyzed on the SpectraStar 2400 Near Infrared Analyzer (Unity Scientific, Columbia, MD, USA), and then sent for primary chemical analysis for fat, protein and carbohydrate. Forty-two samples were used to create a calibration file. Ten samples were then used to validate the machine.Result: After logistic regression analysis, the validation set had a correlation (r 2 ) of 0.91 for carbohydrates, 0.95 for fat and 0.95 for protein. Conclusion:This study demonstrates the feasibility of the use of NIR for nutrient analysis of human milk. NIR offers the potential for analysis and adjustable fortification of human milk to optimize nutrient intake for the high-risk neonate.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Human milk macronutrient analysis using point-of-care near-infrared spectrophotometry

Sauer

Kim

2010

J Perinatol

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“…Recém-nascidos de baixo peso e livres de outras patologias sintomáticas que receberam leite materno tiveram menor tempo de internação e menor perda de peso do que aqueles que foram alimentados por fórmula láctea 4 . Da mesma forma, tem-se observado diminuição do risco de doenças agudas e crônicas [5][6][7] e aumento da sobrevida de crianças nascidas com muito baixo peso em aleitamento materno 8 .…”

Section: Métodos: Foram Estudados Prontuários Médicos De 495 Recém-naunclassified

Exclusive breastfeeding at the point of discharge of high-risk newborns at a Neonatal Intensive Care Unit and the factors associated with this practice

Bicalho-Mancini¹,

Velásquez-Meléndez²

2004

J Pediatr (Rio J)

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Este trabalho é parte da Dissertação de Mestrado defendida por Paula G. Bicalho-Mancini junto ao Curso de Mestrado em Enfermagem, UFMG.Artigo submetido em 19.12.03, aceito em 03.03.04. AbstractObjective: To study the rate of exclusive breastfeeding at the moment of hospital discharge of newborns admitted to a neonatal Intensive Care Unit and to analyze potential risk factors.Methods: Four hundred and ninety-five medical records were studied, pertaining to neonates born between 1998 and 1999, admitted to a neonatal intensive care unit, before and after the implementation of the Baby Friendly Hospital Initiative policies. Babies born during the Baby Friendly Hospital Initiative transition period and outside the Maternity ward were excluded from the study, as were children or mothers who were transferred from the institution, abandoned children and also mothers unfit to breastfeed. Risk factors for non-exclusive breast-feeding at discharge were studied. Odds ratio and 95% confidence intervals were calculated using multivariate logistic regression. Results:The exclusive breastfeeding rate increased from 36% at discharge (before the Baby Friendly Hospital Initiative) to 54.7% (after BFHI). The independent risk factors associated with non-exclusive breastfeeding were the use of enteral feeding (OR = 3.01), ante-natal consultations < 6 (OR = 2.75), relactation use (OR = 2.66), birth weight < 2,500 g (OR = 2.64) and being born during the period before Baby Friendly policies were implemented (OR = 2.75)Conclusion: This research shows the potential efficiency of adopting Baby-Friendly policies to increase the chance of successful breastfeeding at the point of discharge for high-risk newborns. ResumoObjetivo: Avaliar as taxas e o padrão de aleitamento materno dos recém-nascidos internados em berçário de alto risco no momento de sua alta hospitalar e analisar os potenciais fatores que interferem na prática do aleitamento materno exclusivo.Métodos: Foram estudados prontuários médicos de 495 recém-nascidos internados no berçário de alto risco da Maternidade Odete Valadares, Minas Gerais, antes e após receber o título de Hospital Amigo da Criança. Foram excluídos os nascidos fora da maternidade e durante o período de transição, crianças ou mães que foram a óbito ou transferidas da instituição e crianças abandonadas e/ou de mães com contra-indicação para amamentar. Foram calculadas razões de chance (odds ratio, OR) e intervalos de confiança de 95% a partir de análises bivariadas e multivariadas utilizando a técnica da regressão logística.Resultados: A taxa de aleitamento materno exclusivo na alta passou de 36% no período anterior para 54,6% no período posterior à implementação da Iniciativa Hospital Amigo da Criança. Os fatores de risco independentemente associados com ausência de aleitamento exclusivo foram: uso da dieta por sonda (OR = 3,01), número de consultas pré-natais menor que seis (OR = 2,21), uso de translactação (OR = 2,66), peso ao nascer < 2.500 g (OR = 2,64) e internação em período anterior ao recebimento do títu...

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“…This carotenoid may protect the neonate's retina from light-induced oxidative damage that it may encounter in the first months of life (9,10) ; indeed, in this period, lutein in breast milk may help to accommodate the newborn's transition from the darkness experienced in utero.…”

mentioning

confidence: 99%

Lutein concentration in human milk during early lactation and its relationship with dietary lutein intake

Cena

Castellazzi

Pietri

et al. 2009

Public Health Nutr.

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Objective: The present study aimed to estimate the lutein concentration in human milk during early lactation and its relationship with dietary lutein intake measured through the administration of a short FFQ. Design: A cross-sectional study in which an FFQ was administered twice: on day 3 (T0) and day 30 (T1) postpartum; meanwhile two breast milk samples were collected. Maternal plasma samples were obtained at T0. The comparison of dietary lutein intakes and likewise lutein concentrations in breast milk at T0 and T1 were analysed with Student's t test. Pearson's correlation coefficient was used to determine the association between dietary lutein intake and lutein concentration in milk and plasma, respectively, as well as the correlation between breast milk and plasma lutein concentrations at T0. Setting: Pavia, northern Italy. Subjects: Twenty-one pregnant women, age range 24-42 years, were recruited during their last trimester on a voluntary basis. Results: Both breast milk and plasma lutein concentrations were significantly correlated with dietary lutein intake (r 5 0?86, P 5 0?0001 and r 5 0?94, P 5 0?0001, respectively). There was a clear significant correlation between milk and plasma lutein concentrations (r 5 0?87, P 5 0?0001). Mature milk lutein concentration, although significantly reduced at T1 (P , 0?01), maintained a fairly high correlation with dietary lutein intake (r 5 0?82, P 5 0?0001). Conclusions: Even though milk lutein concentration decreased during early lactation, it remained significantly correlated with daily lutein intake. Therefore, while awaiting further research, dietary recommendations advising intake of fresh fruit and vegetables rich in lutein, throughout the whole duration of pregnancy and lactation, are extremely useful.

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Association of Human Milk Feedings With a Reduction in Retinopathy of Prematurity Among Very Low Birthweight Infants

Cited by 167 publications

References 31 publications

Human milk macronutrient analysis using point-of-care near-infrared spectrophotometry

Human milk macronutrient analysis using point-of-care near-infrared spectrophotometry

Exclusive breastfeeding at the point of discharge of high-risk newborns at a Neonatal Intensive Care Unit and the factors associated with this practice

Lutein concentration in human milk during early lactation and its relationship with dietary lutein intake

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