Association of hypertension and diabetic retinopathy in type 2 DM patients.

Ali, Saqib; Sarfraz, Muhammad; Anwar, Touseef; Alam, Muhammad Absar; Khan, Rizwan Rasul; Zafar, Zafar Ali

doi:10.29309/tpmj/2020.27.10.4334

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…10 The desirable value of diastolic pressure below 80 mm of Hg and systolic pressure below 130 mm of Hg has proposed by same study to minimize the vascular risk. 11 The mean/median systolic and diastolic blood pressure of our both study group were in conation with suggested values supporting the role of good blood pressure control in DR.…”

Section: Uk Prospective Diabetes Study Hypertensionsupporting

confidence: 73%

Association of blood pressure with diabetic retinopathy and its severity in patients of type-II diabetes.

Ijaz¹,

Bahoo

Karamat³

et al. 2021

TPMJ

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Objective: To identify the association of blood pressure with DR and its severity in type two diabetics. Study Design: Descriptive, Correlational study. Setting: Outpatient Department of Layton Rahmatulla Benevolent Trust Eye Hospital, Lahore. Period: 1st July, 2016 to 30th August, 2016. Materials & Method: After recording of demographic data, 80 type two diabetics of age 45-65 years of both genders were evaluated by consultant ophthalmologist for status and grading of diabetic retinopathy. Blood pressure was recorded with the help of mercury sphygmomanometer. Data were entered and analyzed on SPSS version 22. Qualitative variables were mentioned as percentages. For comparison of quantitative variables, student ”t” test or mann whiten U test as per distribution of data, were applied. For exploring the association between blood pressure and diabetic retinopathy, spearman rho correlation test was employed. Results: Out of total 80 patients, 42 had DR of varying grade. Most of the study participants were females (62.5 %). On comparison between two groups, systolic blood pressure was not significantly different however, diastolic blood pressure had significant difference. Both systolic and diastolic blood pressure had significant association with severity of DR in both eyes of the patients with only exception of diastolic blood pressure with severity in left eye, which had non-significant correlation. Conclusion: The study results suggest that, blood pressure should be considered as a contributing factor for development and progression of diabetic retinopathy.

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Section: Uk Prospective Diabetes Study Hypertensionsupporting

confidence: 73%

Association of blood pressure with diabetic retinopathy and its severity in patients of type-II diabetes.

Ijaz¹,

Bahoo

Karamat³

et al. 2021

TPMJ

View full text Add to dashboard Cite

show abstract

“…Duration of diabetes, glycemic level, hypertension, hyperlipidemia, nephropathy, and neuropathy are powerful risk factors for the development and severity of retinopathy [7][8][9][10][11]. Although controlling these risk factors is important for the prevention of retinopathy, its development or progression rate is di cult to predict.…”

Section: Introductionmentioning

confidence: 99%

Relationship of Central Corneal Thickness and Central Corneal Epithelial Thickness with Anthropoemetric and Biochemical Data in Individuals with Impaired Glucose Metabolism

Boyacı

Demirci

2023

Preprint

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Background Measure central corneal thickness (CCT) and central corneal epithelial thickness (CCET) with anterior segment-optical coherence tomography (AS-OCT) in individuals with impaired glucose metabolism and to analyze, the effect of impaired glucose metabolism on the cornea.Methods 140 eyes of 70 participants, including 20 healthy controls, 17 insulin resistant, and 33 prediabetic, were evaluated by AS-OCT. Glucose metabolism was examined using a 2-hour 75 g oral glucose tolerance test and glycated haemoglobin A1c (HbA1c). Anthropoemetric measurements, physical examinations, and blood pressure were recorded of all participants. The biochemical parameters were studied.Results The mean age of the participants was 37.93 ± 12.30 years, and the mean HbA1c was 5.50 ± 0.38%. CCET measurements were significantly different and higher in the prediabetic group (p < 0.01). A significant positive correlation was found between both CCETR and CCETL and age, HbA1c, and fasting plasma glucose (p < 0.05). There was found a significant positive correlation was found between CCETR and total cholesterol, triglyceride, and low-density lipoprotein (p < 0.05). Anthropoemetric parameters were significantly different in prediabetics (p˂0.001 and p˂0.05). There was a significant negative correlation between body fat percentage and CCT (p˂0.05). CCET showed a significant positive correlation with neck circumference (p < 0.05).Conclusions It may be suggested that impaired metabolic processes during prediabetes may affect CCET. We believe that prediabetes detection should not be limited to HbA1c and OGTT; A multifactorial algorithm could be developed. AS-OCT may be an easily accessible and useful tool for the early diagnosis of prediabetes.

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Relationship of Central Corneal Thickness and Central Corneal Epithelial Thickness with Anthropoemetric and Biochemical Data in Individuals with Impaired Glucose Metabolism

Boyacı

Demirci

2023

Preprint

View full text Add to dashboard Cite

Background Measure central corneal thickness (CCT) and central corneal epithelial thickness (CCET) with anterior segment-optical coherence tomography (AS-OCT) in individuals with impaired glucose metabolism and to analyze, the effect of impaired glucose metabolism on the cornea. Methods 140 eyes of 70 participants, including 20 healthy controls, 17 insulin resistant, and 33 prediabetic, were evaluated by AS-OCT. Glucose metabolism was examined using a 2-hour 75 g oral glucose tolerance test and glycated haemoglobin A1c (HbA1c). Anthropoemetric measurements, physical examinations, and blood pressure were recorded of all participants. The biochemical parameters were studied. Results The mean age of the participants was 37.93±12.30 years, and the mean HbA1c was 5.50±0.38%. CCET measurements were significantly different and higher in the prediabetic group (p<0.01). A significant positive correlation was found between both CCETR and CCETL and age, HbA1c, and fasting plasma glucose (p<0.05). There was found a significant positive correlation was found between CCETR and total cholesterol, triglyceride, and low-density lipoprotein (p<0.05). Anthropoemetric parameters were significantly different in prediabetics (p˂0.001 and p˂0.05). There was a significant negative correlation between body fat percentage and CCT (p˂0.05). CCET showed a significant positive correlation with neck circumference (p<0.05). Conclusions It may be suggested that impaired metabolic processes during prediabetes may affect CCET. We believe that prediabetes detection should not be limited to HbA1c and OGTT; A multifactorial algorithm could be developed. AS-OCT may be an easily accessible and useful tool for the early diagnosis of prediabetes.

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Association of hypertension and diabetic retinopathy in type 2 DM patients.

Cited by 3 publications

References 10 publications

Association of blood pressure with diabetic retinopathy and its severity in patients of type-II diabetes.

Association of blood pressure with diabetic retinopathy and its severity in patients of type-II diabetes.

Relationship of Central Corneal Thickness and Central Corneal Epithelial Thickness with Anthropoemetric and Biochemical Data in Individuals with Impaired Glucose Metabolism

Relationship of Central Corneal Thickness and Central Corneal Epithelial Thickness with Anthropoemetric and Biochemical Data in Individuals with Impaired Glucose Metabolism

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