Association of IgE elevation with blood group in COVID-19 patients

Abstract

Aim : All parameters that are thought to be efficient in getting sick and follow-up of the disease should be investigated because of COVID-19 disease has serious consequences. The aim of this study was to investigate whether there is a relationship between the AB0 blood group with Rh factor systems and the frequency of catching COVID-19 infection and between IgE elevation according to blood groups and COVID-19 positivity.
 Material and Method: Blood groups and IgE levels of the control group (2690 patients) were compared retrospectively with 7300 patients who were admitted to our hospital between March 10, 2020, and March 31, 2021, and confirmed as COVID-19 positive with viral ribonucleic acid reverse transcriptase-polymerase chain reaction (RT-PCR).
 Results: It was found that among the blood groups, the highest COVID-19 positivity belonged to the A blood group (46.17%) and the lowest belonged to the AB blood group (9.04%). The increase in IgE elevation was found statistically significant in COVID-19 positive patients (P

Differential antibody response to COVID-19 disease and COVID-19 vaccines

“…Number of vaccinated people >200 IU/ml titer N (%) 4 doses CoronaVac [1] 25 4 (16.00) 4 doses [2] 20 7 (35.00) 3 doses CoronaVac [3] 60 6 (10.00) 3 doses BioNTech [4] 30 6 (20.00) 2 CoronaVac +1 BioNTech [5] 47 7 (14.89) 2 doses CoronaVac [6] 110 5 (4.54) 2 doses BioNTech [7] 89 7 (7.86) 4).…”

“…The RNA genome of the virus forms a complex with the nucleocapsid protein. 1,4 It has been stated that the genome structure of SARS-CoV2 and SARS-CoV is 79% similar, and approximately 50% similar to MERS-CoV. 5 SARS-CoV-2 is transmitted through droplets, and the virus attaches to the ACE-2 (angiotensin converting enzyme) receptors on the outer part of the host cell membrane through the S protein during viral entry and multiplies rapidly.…”