Association of Iris Structural Measurements with Corneal Biomechanics in Myopic Eyes

Фу, Лин; Ye, Yufeng; Xu, Jia; Zhang, Yunjie; Chen, Xiaoyu; Lian, Hengli; Yang, Weihua; Dai, Qi

doi:10.1155/2021/2080962

Cited by 4 publications

(2 citation statements)

References 22 publications

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“… 37 – 39 It has also been reported that corneal biomechanical properties are related to retinal deformation 40 and iris sectional parameters. 41 , 42 This may be due to the deformation of the sclera, which dominates the eyeball nonuniform deformation, leading to corneal mechanical properties connected with other tissue characteristics.…”

Section: Discussionmentioning

confidence: 99%

Corneal Biomechanical Properties Demonstrate Anisotropy and Correlate With Axial Length in Myopic Eyes

Chen,

Huang,

Zhang

et al. 2023

Invest. Ophthalmol. Vis. Sci.

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Purpose The purpose of this study was to investigate the ex vivo and in vivo biomechanical characteristic of cornea in myopic eyes. Methods Fifty-one corneal stromal lenticules were obtained from myopic eyes during the SMILE procedure and were tested by a biaxial tensile system within 24 hours postoperatively. The material properties of the lenticules were described using stress-strain curves and were compared among axial length (AL) <26 mm and AL ≥ 26 mm group. Pre-operative stress-strain index (SSI) parameters were used to evaluate the biomechanical properties of the cornea in vivo. Results Compared with AL < 26 mm, the tangent modulus significantly decreased in horizontal and vertical directions when AL ≥ 26 mm ( P < 0.05); SSI also significantly decreased when AL ≥ 26 mm ( P < 0.05). Anisotropic parameter is positively correlated with AL ( r = 0.307, P < 0.05). Compared with AL < 26 mm, anisotropic parameter significantly increased when AL ≥ 26 mm ( P < 0.05). SSI was negatively correlated with AL ( r = −0.380, P < 0.05) in the AL < 26 mm group but not in the AL ≥ 26 mm group ( P > 0.05). Compared with 26 mm ≤ AL < 27 mm group, the tangent modulus significantly decreased in the horizontal direction ( P < 0.05) but not in the vertical direction when 27 mm ≤ AL < 28 mm ( P > 0.05). Conclusions The biomechanical properties of cornea decreased with the increase of AL. Tangent modulus significantly decreased in the horizontal direction compared with vertical direction. AL should be taken into account during calculation of corneal biomechanical parameters in order to improve validity.

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Section: Discussionmentioning

confidence: 99%

Corneal Biomechanical Properties Demonstrate Anisotropy and Correlate With Axial Length in Myopic Eyes

Chen,

Huang,

Zhang

et al. 2023

Invest. Ophthalmol. Vis. Sci.

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“…High myopia is more likely to be accompanied by structural abnormalities of the anterior chamber, such as deep anterior chamber depth and concave iris [ 6 ]. Concave iris is a typical characteristic of pigment dispersion syndrome [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Primary observations of EVO ICL implantation for high myopia with concave iris

et al. 2023

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Purpose To investigate the morphological changes of concave iris in myopic patients after EVO implantable collamer lens (ICL) implantation. Methods EVO ICL candidates with posterior bowing iris were observed using ultrasound biometric microscopy (UBM) in this prospective nonrandomized observational study. Forty patients were enrolled, with 20 patients in the concave iris group and the other 20 patients in the control group. None of the patients underwent laser peripheral iridotomy. All patients received preoperative and postoperative examinations, which included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), subjective manifest refraction and intraocular pressure. UBM was used to observe iris curvature (IC), irido-corneal angle (ICA), posterior chamber angle (PCA), iris-lens contact distance (ILCD), iris-zonule distance (IZD) and ciliary process length (CPL). Anterior chamber angle pigment was observed by gonioscopy. The preoperative and postoperative data were analyzed using SPSS. Results The average follow-up period was 13.3 ± 5.3 months. The mean efficacy indices were 1.10 ± 0.13 and 1.07 ± 0.11 (P = 0.58), and the safety indices were 1.19 ± 0.09 and 1.18 ± 0.17 in the control group and the concave iris group (P = 0.93), respectively. The IOP postoperatively were 14.13 ± 2.02 mmHg and 14.69 ± 1.59 mmHg in control and concave iris groups (P = 0.37). Preoperatively, the concave iris group was presented with greater IC (P < 0.0001), longer ILCD (P < 0.0001), wider ICA (P = 0.004), narrower PCA (P = 0.01), and shorter IZD (P = 0.03) than the control group. In the concave iris group, IC, ILCD and ICA were significantly decreased after ICL implantation (P < 0.0001), while PCA and IZD were significantly increased (P = 0.03 and P = 0.04, respectively). Postoperative IC, ILCD, ICA, PCA and IZD were not statistically different between groups (P > 0.05). There was no significant difference in pigment deposition grades between the two groups (P = 0.37). Conclusion After EVO ICL implantation, the morphology of concave iris was significantly improved, which may reduce the risk of intraocular pigment dissemination caused by iris concavity. The concave iris has no impact on the safety of EVO ICL surgery during the follow-up.

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The corneal biomechanical differences after wearing orthokeratology lenses and multifocal soft lenses in children: A self-control study

Fu,

Jiang,

Lian

et al. 2024

Contact Lens and Anterior Eye

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Association of Iris Structural Measurements with Corneal Biomechanics in Myopic Eyes

Cited by 4 publications

References 22 publications

Corneal Biomechanical Properties Demonstrate Anisotropy and Correlate With Axial Length in Myopic Eyes

Corneal Biomechanical Properties Demonstrate Anisotropy and Correlate With Axial Length in Myopic Eyes

Primary observations of EVO ICL implantation for high myopia with concave iris

The corneal biomechanical differences after wearing orthokeratology lenses and multifocal soft lenses in children: A self-control study

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