Association of Life’s Essential 8 With Incident Cardiovascular Disease Among Individuals With Depression: A Prospective Study

Chen, Qian; Zhao, Wanying; Zhang, Qi; Li, Siqi; Zhao, Jiaqi; Chen, Wanlan; Xia, Min; Liu, Yan

doi:10.1016/j.cjca.2024.08.280

Canadian Journal of Cardiology

2024

DOI: 10.1016/j.cjca.2024.08.280

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Association of Life’s Essential 8 With Incident Cardiovascular Disease Among Individuals With Depression: A Prospective Study

Qian Chen,

Wanying Zhao,

Qi Zhang

et al.

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2024

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Investigating the Impact of the Number of Medication Use on Depression Among Hypertensive Patients: Results from the National Health and Nutrition Examination Survey Database

Alsulami,

Almalki,

Algarni

et al. 2024

Medicina

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Background and Objective: Hypertension is a prevalent chronic condition often treated with multiple medications, leading to polypharmacy, which can heighten the risk of adverse drug reactions and contribute to psychological issues like depression. This study aimed to investigate the relationship between polypharmacy and depressive symptoms in hypertensive patients using data from the National Health and Nutrition Examination Survey (NHANES) from 2017 to 2020. Materials and Methods: This study utilized data from the National Health and Nutrition Examination Survey (NHANES) collected between 2017 and March 2020. Results: Among 2543 hypertensive participants, 12.3% met the criteria for depression. The findings revealed that patients using 11 or more medications were ten times more likely to experience depressive symptoms compared to those taking 1 to 2 medications (OR = 10.06, p < 0.001). Additionally, younger age (18 to 45 years), female gender, and lower educational attainment were significantly associated with higher rates of depressive symptoms. Specifically, females were 1.47 times more likely to experience depression compared to males (p = 0.032). Conclusions: This research highlights the substantial impact of medication burden on mental health among hypertensive patients, emphasizing the need for tailored clinical interventions for this vulnerable population.

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Investigating the Impact of the Number of Medication Use on Depression Among Hypertensive Patients: Results from the National Health and Nutrition Examination Survey Database

Alsulami,

Almalki,

Algarni

et al. 2024

Medicina

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show abstract

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Association of Life’s Essential 8 With Incident Cardiovascular Disease Among Individuals With Depression: A Prospective Study

Cited by 1 publication

References 31 publications

Investigating the Impact of the Number of Medication Use on Depression Among Hypertensive Patients: Results from the National Health and Nutrition Examination Survey Database

Investigating the Impact of the Number of Medication Use on Depression Among Hypertensive Patients: Results from the National Health and Nutrition Examination Survey Database

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