Association of Mean Platelet Volume and Platelet Distribution Width with Hba1c

Jaman, Sadikuj

doi:10.15226/2374-6890/4/4/00183

Cited by 16 publications

(16 citation statements)

References 33 publications

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“…WBC count is positively associated with increased cardiovascular mortality, mainly from coronary heart disease [35]. Previously our researches have been shown the association of mean platelet volume and platelet parameter with HbA1c [36]. In this study, we aimed to evaluate the relationship between RBC parameter such as RBC count, PCV, MCV, MCHC, RDW-CV and HbA1c value ≥7.5 of diabetics' patients.…”

Section: Introductionmentioning

confidence: 97%

Diabetes and red blood cell parameters

MS¹

2017

Ann Clin Endocrinol Metabol

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Type 2 diabetes is a common disease in these days and day by day it is arising. The main focus of the study was to investigate association of packed cell volume (PCV), Mean Corpuscular Volume (MPV), Mean Corpuscular Hemoglobin Concentration (MCHC), Red Cell Distribution Width (RDW) with glycemic marker HbA1c. So that PCV, MPV, MCHC, RDW could be used as a predictor of glucoregulation in type 2 diabetes instead of HbA1c value. This study included 87 DMT2 patients, which divided into two groups, A (n=41, presence in diabetics≤6.5-6.9%) and B (n=46, target in diabetes≥7.0%), according to HbA1c values. Spearsman correlation co-effi cients were calculated to evaluate the relationship between RBC count, MCHC, RDW with random blood sugar (RBS) and PCV, MCV, MCHC with HbA1c value. Binominal logistic regression analysis was performed to estimate the relationship between glycemic control, as dichotomous outcome of MCHC, RDW, PCV, and MCV as the main prognosticator. MCHC and RDW were signifi cantly higher in the group B compared to the group A. RDW and MCHC may be applied as the auxiliary indicators of deterioration of glucoregulation.

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Section: Introductionmentioning

confidence: 97%

Diabetes and red blood cell parameters

MS¹

2017

Ann Clin Endocrinol Metabol

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“…Some studies have found a significant linear positive correlation between MPV values and HbA1c levels, which indicates the usefulness of MPV in determining the level of glycaemic control. [4,6,12] These studies indicate that MPV can be used as an alternative marker for glycaemic control in type 2 DM. In the present study there was no correlation between MPV and HbA1c.…”

Section: Discussionmentioning

confidence: 82%

“…The cases were divided in three groups based on the level of diabetes control as [6] good control: 6.0-7.0%, fair control: 7.1-8.2%, poor control: above 8.2%.…”

Section: Definition Of Variables: Diabetes Mellitus Was Diagnosedmentioning

confidence: 99%

Relationship of Mean Platelet Volume and HbA1c in Predicting the Level of Diabetes Control in Type 2 Diabetes Mellitus

Varshini

K²

2020

APALM

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Background:MPV is an indicator of platelet size and MPV is increased in DM as compared to non-diabetics, more so in presence of complications. There are few studies evaluating the association between MPV and HbA1c and its role in predicting glycaemic control with conflicting results. The present study was planned to determine the relationship between MPV and HbA1c in predicting the level of diabetes control in type 2 DM.Methodology: Cross sectional observational study including 100 consecutive cases of type 2 DM . Mean platelet volume (MPV), platelet distribution width (PDW) and platelet count were obtained from fully automated haematology analyser Sysmex KX-21. Glycosylated haemoglobin (HbA1c) was analysed by automated haemoglobin analyser. Results:The mean age among 100 type 2 DM cases was 49.58 ± 14.49 years. The mean value of MPV and HbA1c was 10.25±0.90fl and 5.66± 1.17% respectively. There was no significant correlation found between MPV and HbA1c (r=0.110, p=0.275). Similarly, there were no significant association between MPV and three levels of glycaemic control. Conclusion:MPV is not a reliable marker for determining glycaemic control in type 2 DM.

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“…Elevated PDW values have been shown relation with increased mortality in patients with acute coranry syndromes that treated with primary percutaneous coronary intervention (7). Jaman et al (8) studied association between HbA1c; MPV and PDW. They showed that glycemic control markers correlated with MPV and PDW.…”

Section: Resultsmentioning

confidence: 99%

Tip 2 diyabet hastalarında glikolize hemoglobin ve plataletcrit ilişkisi

Doğan

Karahan

2019

Journal of Health Sciences and Medicine

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Amaç: Tip 2 diyabet ciddi damar hastalıklarına yol açabilen bir hastalıktır. Plateletcrit (PCT) anormal düzeyleri yapılan çalışmalarda koroner arter hastalıkları için risk faktörü olarak belirlenmiştir. Glikolize hemoglobin (HbA1c), glisemik kontrolü değerlendirmek için geniş kullanıma sahip bir belirteçtir. Bu çalışmada PCT ile HbA1c arasındaki ilişkinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Çalışma, retrospektif vaka kontrol çalışmasıdır. Tip 2 diyabetli 63 hasta ve benzer özelliklerdeki 51 sağlıklı kontrol grubu bireyin geçmiş kayıtları değerlendirilmiş, iki grup arasında MPV ve PCT düzeyi karşılşatırılmıştır. Diyabetik hastalarda HbA1c ve MPV, PCT arasındaki ilişki araştırılmıştır. Bulgular: Tip 2 diyabetli hastalarda sağlıklı kontrollerle karşılaştırıldığında MPV'de anlamlı fark saptanırken (p<0,001), PCT'de anlamlı fark saptanmadı (p=0.65). HbA1c ve PCT arasında anlamlı korelasyon saptandı (r=0,4 p<0,01). MPV ile korelasyon saptanmadı. Sonuç: PCT, glisemik kontrolü sağlanmayan ve buna bağlı vasküler hasar gelişme olasılığı olan hastalarda yol gösterici olabilir. Bu açıdan, anormal PCT düzeyleri olan hastaların vasküler patolojiler açısından yakın takibi önemli olabilir.

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Association of Mean Platelet Volume and Platelet Distribution Width with Hba1c

Cited by 16 publications

References 33 publications

Diabetes and red blood cell parameters

Diabetes and red blood cell parameters

Relationship of Mean Platelet Volume and HbA1c in Predicting the Level of Diabetes Control in Type 2 Diabetes Mellitus

Tip 2 diyabet hastalarında glikolize hemoglobin ve plataletcrit ilişkisi

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