Association of Objectively Measured Physical Activity and Metabolic Syndrome Among US Adults With Osteoarthritis

Abstract

Objective To investigate the association between objectively-measured physical activity and metabolic syndrome among adults with osteoarthritis (OA). Methods Using cross-sectional data from 2003–2006 NHANES, we identified 566 adults with OA with available accelerometer data assessed using Actigraph AM-7164 and measurements necessary to determine metabolic syndrome by Adult Treatment Panel III. Analysis of variance was conducted to examine the association between continuous variables in each activity level and metabolic syndrome components. Logistic models estimated the relationship of quartile of daily minutes of different physical activity levels to odds of metabolic syndrome adjusted for socioeconomic and health factors. Results Among persons with OA, most were female with average age 62.1 years and average duration of disease of 12.9 years. Half of adults with OA had metabolic syndrome (51.0%; 95% Confidence Interval (CI): 44.2% to 57.8%), and only 9.6% engaged in the recommended 150 minutes per week of moderate/vigorous physical activity. Total sedentary time was associated with higher rates of metabolic syndrome and its components while light and moderate/vigorous objectively-measured physical activity were inversely associated with metabolic syndrome and its components. Higher levels of light activity was associated with lower prevalence of metabolic syndrome (quartile 4 versus quartile 1: adjusted odds ratio: 0.45; 95% CI: 0.24 to 0.84; p-value for linear trend < 0.005). Conclusion Most U.S. adults with OA are sedentary. Increased daily minutes in physical activity, especially in light intensity, is more likely to be associated with decreasing prevalence of metabolic syndrome among persons with OA.

Osteoarthritis‐Related Walking Disability and Arterial Stiffness: Results From a Cross‐Sectional Study

“…However, results from a recent population‐based cohort study showed that hip OA or knee OA is a strong contributor to walking difficulty , and only a small‐to‐moderate proportion of patients with hip OA or knee OA meet the guidelines for physical activity . Many patients with OA spend a considerable amount of time being sedentary, leading to more impairment in physical function, reduced walking speed , and poorer cardiometabolic health compared with their peers who had a less sedentary lifestyle. Therefore, assessment of cardiorespiratory fitness should be prioritized in clinical practice , and improved cardiorespiratory fitness should be a treatment goal, in order to prevent cardiovascular co‐morbidity in OA.…”

Exercise in bipolar patients: A systematic review

“…Studies about the effects of physical activity on the metabolic syndrome in bipolar patients showed uncertain results. Similarly to other physical and mental conditions (Kahl et al, 2015;Liu et al, 2015;Park and Larson, 2014), physical activity should improve anthropometric measures and impact positively on metabolic syndrome. Possibly, an explanation for the few available studies may be the difficulty in recruiting and the adherence to physical exercise in bipolar population with frequent severe behavioral symptoms.…”

The longitudinal relationship between hand, hip and knee osteoarthritis and cardiovascular events: a population-based cohort study

“…Obesity, dyslipidemia, impaired fasting glucose, and hypertension have been hypothesized to contribute to OA incidence and progression 8,9 and, in turn, OA has been hypothesized as an independent 'metabolic' risk factor for CVD. A number of cross-sectional studies have demonstrated a positive association between the presence of OA, variably defined, and both metabolic syndrome and CVD 4,5,10 ; these relationships appear stronger for hand and knee OA than for hip OA. More recently, it has also been shown in longitudinal studies that people with symptomatic hip, knee, and possibly hand OA are at increased risk for CVD 11e13 relative to the age-and sex-matched general population or to non-OA controls.…”