Association of Obstructive Sleep Apnea Risk or Diagnosis with Daytime Asthma in Adults

Relation between obstructive airway disease and body mass index, neck circumference in patients with obstructive sleep apnoea

“…Again, several overlapping pathways may be at play in this direction as well. 17,18 Flenley considered that multiple respiratory diseases could "overlap" in the same individual. 6 The association of COPD and OSA was defined as Overlap Syndrome.…”

Nocturnal Asthma: A Special Type of Asthma

“…While nocturnal allergen exposure does not explain nocturnal asthma symptoms in general, dust mite, dog/cat, and other sensitivities must be considered in individual patients, and interventions should be taken, ranging from elimination to desensitization [37,38].…”

Control of asthma in real life: still a valuable goal?

“…The most common comorbidities that complicate asthma control are allergic rhinitis [30], gastro-oesophageal reflux disease (GORD) [31], obstructive sleep apnoea [32] and psychopathological comorbidities [33]. Allergic rhinitis often coexists with asthma and probably over 80% of patients with allergic asthma have concomitant rhinitis [30].…”

“…Thus, treatment with proton pump inhibitors is not expected to improve poorly controlled asthma unless a patient suffers from symptomatic GORD [1,40]. Obstructive sleep apnoea is another comorbidity that can be present in asthmatic patients and is related to increased asthma symptoms and poor asthma control [32]; sleep apnoea management with continuous positive airway pressure results in improvement of asthma control [41]. In a pivotal study from the Netherlands, factors significantly associated with frequent exacerbations included severe nasal sinus disease (adjusted odds ratio (OR) 3.7), gastro-oesophageal reflux (OR 4.9), recurrent respiratory infections (OR 6.9) and obstructive sleep apnoea (OR 3.4).…”