2018
DOI: 10.21608/smj.2018.42049
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Association of osteopontin promoter polymorphism and aggresivness in breast cancer

Abstract: Background. Osteopontin (OPN) is an extracellularmatrix protein that is overexpressed in various cancers and promotes onco-genic features including cell proliferation, survival, migration, and angiogenesis. Here, we analyzed the correlation between the expression pattern of (osteopontin and CA15.3) and clinic-pathological status of breast cancer and other standard prognostic factors. Patients and methods. A case control study with 60 female breast cancer patients and 20 controls. All patients were subjected to… Show more

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