Association of physical activity on the functional connectivity of the hippocampal–orbitofrontal pathway

Ikuta, Toshikazu; Frith, Emily; Ponce, Pamela; Loprinzi, Paul D.

doi:10.1080/00913847.2018.1549461

Cited by 14 publications

(17 citation statements)

References 37 publications

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“…Specifically, we found that PA is linked to increased connectivity between the middle/posterior hippocampal activation cluster and regions of the default mode network. This is in accordance with many previous results reported in the literature (Tao et al, 2016;Ikuta et al, 2019;Prakash et al, 2011;Esteban-Cornejo et al, 2021;Voss, Erickson, et al, 2010;Voss, Prakash, et al, 2010;Voss et al, 2016;Burdette et al, 2010;Boraxbekk et al, 2016;Weng et al, 2017). In addition, we found that PA is associated with a decreased connectivity between an anterior hippocampal activation cluster and areas typically involved in the somatomotor network.…”

Section: Discussionsupporting

confidence: 93%

“…To sum up, previous research on PA had shown that PA produces changes in the structure and function of the hippocampus (K. Erickson & Kramer, 2009; A. Thomas et al, 2012;Tao et al, 2016;Ikuta et al, 2019;Esteban-Cornejo et al, 2021;Voss, Erickson, et al, 2010;Boraxbekk et al, 2016;Kern et al, 2021) but had barely addressed whether…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, rsfMRI studies examining functional connectivity in elderly have shown that PA produces changes in the way the hippocampus co-activates with other large-scale networks (e.g., Weng et al, 2017). Specifically, studies consistently find increased hippocampal connectivity to various default mode network areas such as anterior and posterior midline areas, as well as with motor areas (Tao et al, 2016;Ikuta et al, 2019;Prakash et al, 2011;Esteban-Cornejo et al, 2021;Voss, Erickson, et al, 2010;Voss, Prakash, et al, 2010;Voss et al, 2016;Burdette et al, 2010;Boraxbekk et al, 2016;Weng et al, 2017). For example, Voss, Prakash, et al (2010) studied the effects of 3-times-per-week 1-year-long interventions for both aerobic and non-aerobic exercise in groups of elderly participants.…”

Section: Introductionmentioning

confidence: 99%

“…In terms of the functional connectivity of the hippocampus with the rest of the brain, most previous studies have examined how PA affected the relationship between the hippocampus and the default mode network (Tao et al, 2016;Ikuta et al, 2019;Prakash et al, 2011;Esteban-Cornejo et al, 2021;Voss, Erickson, et al, 2010;Voss, Prakash, et al, 2010;Voss et al, 2016;Burdette et al, 2010;Boraxbekk et al, 2016;Weng et al, 2017). However, it is well-known that the hippocampus co-activates with at least two different whole-brain resting-state networks (Ezama et al, 2021;Kahn et al, 2008;Ranganath & Ritchey, 2012;Vincent et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

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Daily-life Physical Activity of Young Healthy Adults Associates with Function and Structure of the Hippocampus

Seoane¹,

Ezama²,

Janssen³

2021

Preprint

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Research on the impact of physical activity (PA) has shown that PA produces changes in the structure and function of a brain structure called the hippocampus. There are three main limitations in this research. First, the majority of the work has been carried out in elderly populations and as such, there is a paucity of research on the impact of PA on the brains of healthy young individuals. Second, whereas PA is typically assessed through controlled interventions, changes in the brain due to PA as performed during daily-life activities has not been explored. Finally, the hippocampus has a complex internal structure and the impact of PA on this internal structure is unclear. Here we examined how structural and functional aspects of the hip-pocampus are associated with habitual PA performed during work, leisure time and sports in the daily lives of young healthy adults. We found that PA performed during work time correlated with increased subicular volumes and with changed functional connectivity between a location in middle/posterior hippocampus and regions of the default mode network and between a location in anterior hippocampus and regions of the somatomotor network. No effects of PA performed during leisure time and sports were found. The results generalize the impact of PA to younger populations and show how PA performed in daily-life situations correlates with the precise internal structure of the hippocampus.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Daily-life Physical Activity of Young Healthy Adults Associates with Function and Structure of the Hippocampus

Seoane¹,

Ezama²,

Janssen³

2021

Preprint

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“…For example, exercise may help to coordinate neuronal firing in hippocampal circuits and enhance integration of adult-born neurons into existing hippocampal-entorhinal circuity [83]. As we recently demonstrated, exercise may enhance the functional connectivity of key memory-related brain structures (e.g., connectivity between parahippocampi and connectivity of hippocampal-orbitofrontal pathway) [84,85]. Relatedly, structural brain changes have been observed from chronic exercise [86].…”

Section: Discussionmentioning

confidence: 99%

The Temporal Effects of Acute Exercise on Episodic Memory Function: Systematic Review with Meta-Analysis

et al. 2019

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Background: Accumulating research demonstrates that the timing of exercise plays an important role in influencing episodic memory. However, we have a limited understanding as to the factors that moderate this temporal effect. Thus, the purpose of this systematic review with meta-analysis was to evaluate the effects of study characteristics (e.g., exercise modality, intensity and duration of acute exercise) and participant attributes (e.g., age, sex) across each of the temporal periods of acute exercise on episodic memory (i.e., acute exercise occurring before memory encoding, and during memory encoding, early consolidation, and late consolidation). Methods: The following databases were used for our computerized searches: Embase/PubMed, Web of Science, Google Scholar, Sports Discus and PsychInfo. Studies were included if they: (1) Employed an experimental design with a comparison to a control group/visit, (2) included human participants, (3) evaluated exercise as the independent variable, (4), employed an acute bout of exercise (defined as a single bout of exercise), (5) evaluated episodic memory as the outcome variable (defined as the retrospective recall of information either in a spatial or temporal manner), and (6) provided sufficient data (e.g., mean, SD, and sample size) for a pooled effect size estimate. Results: In total, 25 articles met our inclusionary criteria and were meta-analyzed. Acute exercise occurring before memory encoding (d = 0.11, 95% CI: −0.01, 0.23, p = 0.08), during early memory consolidation (d = 0.47, 95% CI: 0.28, 0.67; p < 0.001) and during late memory consolidation (d = 1.05, 95% CI: 0.32, 1.78; p = 0.005) enhanced episodic memory function. Conversely, acute exercise occurring during memory encoding had a negative effect on episodic memory (d = −0.12, 95% CI: −0.22, −0.02; p = 0.02). Various study designs and participant characteristics moderated the temporal effects of acute exercise on episodic memory function. For example, vigorous-intensity acute exercise, and acute exercise among young adults, had greater effects when the acute bout of exercise occurred before memory encoding or during the early memory consolidation period. Conclusions: The timing of acute exercise plays an important role in the exercise-memory interaction. Various exercise- and participant-related characteristics moderate this temporal relationship.

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Comparative electroencephalography analysis: Marathon runners during tapering versus sedentary controls reveals no significant differences

Moussiopoulou,

Handrack‐Bonnet,

Pross

et al. 2024

Brain and Behavior

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IntroductionPrevious studies described various adaptive neuroplastic brain changes associated with physical activity (PA). EEG studies focused mostly on effects during or shortly after short bouts of exercise. This is the first study to investigate the capability of EEG to display PA‐induced long‐lasting plasticity in runners compared to a sedentary control group.MethodsThirty trained runners and 30 age‐ and sex‐matched sedentary controls (SC) were included as a subpopulation of the ReCaP (Running effects on Cognition and Plasticity) study. PA was measured with the International Physical Activity Questionnaire (IPAQ). Resting‐state EEG of the runners was recorded in the tapering phase of the training for the Munich marathon 2017. Power spectrum analyses were conducted using standardized low‐resolution electromagnetic tomography (sLORETA) and included the following frequency bands: delta: 1.5–6 Hz, theta: 6.5–8.0 Hz, alpha1: 8.5–10 Hz, alpha2: 10.5–12.0 Hz, beta1: 12.5–18.0 Hz, beta2: 18.5–21.0 Hz, beta3: 21.5–30.0 Hz, and total power (1.5–30 Hz).ResultsPA (IPAQ) and BMI differed significantly between the groups. The other included demographic parameters were comparable. Statistical nonparametric mapping showed no significant power differences in EEG between the groups.DiscussionHeterogeneity in study protocols, especially in time intervals between exercise cessation and EEG recordings and juxtaposition of acute exercise‐induced effects on EEG in previous studies, could be possible reasons for the differences in results. Future studies should record EEG at different time points after exercise cessation and in a broader spectrum of exercise intensities and forms to further explore the capability of EEG in displaying long‐term exercise‐induced plasticity.

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Association of physical activity on the functional connectivity of the hippocampal–orbitofrontal pathway

Cited by 14 publications

References 37 publications

Daily-life Physical Activity of Young Healthy Adults Associates with Function and Structure of the Hippocampus

Daily-life Physical Activity of Young Healthy Adults Associates with Function and Structure of the Hippocampus

The Temporal Effects of Acute Exercise on Episodic Memory Function: Systematic Review with Meta-Analysis

Comparative electroencephalography analysis: Marathon runners during tapering versus sedentary controls reveals no significant differences

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