Association of physical activity with sleep-disordered breathing

Abstract

This study was performed to determine whether there is a protective association between participation in vigorous or vigorous/moderately vigorous physical activity and the prevalence of sleep-disordered breathing (SDB). Polysomnographic and questionnaire data from the baseline examination of 4,275 participants in the Sleep Heart Health Study (SHHS) were analyzed in relation to information on amount of physical activity and other potentially relevant factors collected from five SHHS parent cohorts (Atherosclerosis Risk in Communities Study, Cardiovascular Health Study, Framingham Heart Study, Strong Heart Study, and Tucson Epidemiologic Study of Airways Obstructive Diseases). Logistic regression models were fitted to determine if amount and strenuousness of physical activity was associated with the presence of SDB. At least 3 h per week of vigorous physical activity reduced the odds of SDB, defined as a respiratory disturbance index (RDI) of at least 15 apneas/hypopneas per hour (Adjusted OR, 0.68; 95%CI, 0.51-0.91). A qualitatively similar but slightly weaker association was observed when SDB was defined as a RDI > or = 10 per hour (Adjusted OR, 0.81; 95%CI, 0.64-1.02). These findings remained after adjustment for sleepiness and restricting analyses to participants with good health. Three or more hours of moderately vigorous or vigorous physical activity also appeared to confer some protection against SDB, but these associations were weaker. Gender- and obesity-stratified analyses suggested that the protective association between physical activity and SDB occurred primarily in men and those who were obese. A program of regular vigorous physical activity of at least 3 h per week may be a useful adjunctive treatment modality for SDB, but this association needs confirmation with a prospective clinical trial.

Physical Inactivity Is Associated with Moderate-Severe Obstructive Sleep Apnea

“…Consistent with the findings of this study, previous large community-based samples have reported an association between exercise and reduced risk of OSA. In some of these previous findings, such an association did not persist after accounting for body habitus, 6,11 while in others an association remained.…”

“…11 However, unlike the Sleep Heart Health Study, 23 the present study examined occupational activity and exercise, employed a single validated exercise activity questionnaire, and had a larger OSA group. As a result, the present study was able to define nil and low exercise categories.…”

“…Exercise activity may positively modulate OSA by increase of upper airway tonus via the recruitment of upper airway muscles for breathing work or head stability. 27,28 Studies examining the effect of physical activity on OSA have not measured muscle tonus, 6,10,11 but instead have examined the mediating effect of obesity. Similarly, methods that have been developed to increase upper airway tonus for the treatment of OSA have not been proven effective.…”

“…10,11 To date, most exercise studies have not captured range of exercise intensities, preferring to dichotomize samples by comparing the effect of vigorous exercise with all other activity levels taken as baseline. 6,11 Only one community sample of OSA subjects has defi ned nil exercise as a separate category from low levels of exercise where, using nil exercise as baseline, there were BRIEF SUMMARY Current Knowledge/Study Rationale: Physical inactivity is increasingly recognised as a health risk factor but it is largely unknown whether such inactivity is associated with OSA and, if so, the health consequences for patients with this condition. Study Impact: Vigorous exercise may protect against the development of moderate-severe OSA while low or no exercise could contribute to its occurrence.…”

The Diagnostic Value of Pleural Fluid Neopterin Level in Tuberculous Pleurisy

“…Literatürde yer alan çal malarda ya , vücut kitle indeksi, fiziksel aktivite al kanl ve e itim durumunun solunum fonksiyonlar n , egzersiz kapasitesini ve ya am kalitesi düzeyini etkileyebilece i bildirilmektedir [14][15][16]. Bu nedenle; sosyodemografik özellikler ve hava yolu obstrüksiyon iddetini gösteren FEV 1 de eri aç s ndan çal -maya dahil etti imiz her iki hastal k grubundaki hastalar n benzer özelliklere sahip olmas n n verilerin kar la t rmas nda kolayl k sa lad dü ünülmektedir.…”