2007
DOI: 10.1097/ppo.0b013e31813fffdd
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Association of Polymorphisms of FAS-1377, FAS-670, and FASL-844 Genes With Risk Factors for Cutaneous Malignant Melanoma

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“…This functionality may influence FAS-mediated apoptosis and therefore lead to different individual susceptibility of cancer. It was demonstrated that these polymorphisms are associated with a higher risk of developing breast cancer, squamous cell carcinoma of the head and neck, bladder cancer, T-cell leukaemia, lung cancer, cutaneous malignant melanoma, prostate cancer, cervical cancer, esophageal squamous cell carcinoma and acute myeloid leukaemia [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. The FAS -670A/G polymorphism showed to have a correlation with survival in adult T-cell leukaemia as well [26].…”
mentioning
confidence: 99%
“…This functionality may influence FAS-mediated apoptosis and therefore lead to different individual susceptibility of cancer. It was demonstrated that these polymorphisms are associated with a higher risk of developing breast cancer, squamous cell carcinoma of the head and neck, bladder cancer, T-cell leukaemia, lung cancer, cutaneous malignant melanoma, prostate cancer, cervical cancer, esophageal squamous cell carcinoma and acute myeloid leukaemia [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25]. The FAS -670A/G polymorphism showed to have a correlation with survival in adult T-cell leukaemia as well [26].…”
mentioning
confidence: 99%