Association of Puberty Stage and Weight Status with Cardiometabolic Risk in Children and Adolescents Living on the Texas-Mexico Border

Low, Ee Vien; Lee, Miryoung; Bauer, Cici; Fisher‐Hoch, Susan P.; McCormick, Joseph B.; Abughosh, Susan; Essien, Ekere James; Rodriguez, Jessica; Chen, Hua

doi:10.1089/met.2021.0151

Cited by 4 publications

(3 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The relationship between obesity and hypertension is well established [80]. Considering the obesity epidemic, there appeared a risk that the normal values and subsequently the thresholds defining hypertension would be higher if new nomograms were created based on studies carried out in more recent years.…”

Section: Insulin and Insulin Resistancementioning

confidence: 99%

“…Linear growth and bone maturation usually is accelerated in prepubertal children with obesity, however, subsequently there is a reduction of pubertal height gain such that any advantage in linear growth is lost and their final height does not differ from non-obese children [ 79 ]. The relationship between obesity and hypertension is well established [ 80 ]. Considering the obesity epidemic, there appeared a risk that the normal values and subsequently the thresholds defining hypertension would be higher if new nomograms were created based on studies carried out in more recent years.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of Puberty on Blood Pressure Trajectories — Underlying Processes

et al. 2023

View full text Add to dashboard Cite

Puberty is a complex process leading to physical, sexual, and psychosocial maturation. The changes in morphology and organ function during puberty also affect blood pressure (BP) regulation, and as a consequence (BP) values change noticeably, reaching values often higher than after reaching full maturity. In children entering puberty, BP, especially systolic, increases and then reaches adult values by the end of puberty. The mechanisms responsible for this process are complex and not fully understood. Sex hormones, growth hormone, insulin-like growth factor-1, and insulin, whose production increases during puberty, significantly regulate BP through complex and overlapping mechanisms. During puberty, the incidence of arterial hypertension also increases, especially in children with excess body weight. The present paper presents the current state of knowledge regarding the influence of processes occurring during puberty on blood pressure.

show abstract

Section: Insulin and Insulin Resistancementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of Puberty on Blood Pressure Trajectories — Underlying Processes

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Doors are opened for them, which would never be opened for the investigators [4,17]. This cohort has been followed since 2004, and the team has remained with the project, acquiring not only advanced skills (ultrasound, FibroScan, retinal photos, measures of cognition, mental health, DEXA) but are also able to communicate with people and deriv information that otherwise might be withheld [18][19][20][21][22]. Currently, we are conducting an NIHfunded study using a semaglutide in prediabetes, and recruitment in the hands of our staff is not a problem.…”

Section: Experiences and Storiesmentioning

confidence: 99%

Challenges and strategies for recruitment of minorities to clinical research and trials

Fisher‐Hoch¹,

Below²,

North³

et al. 2023

J. Clin. Trans. Sci.

Self Cite

View full text Add to dashboard Cite

Minority populations are largely absent from clinical research trials. The neglect of these populations has become increasingly apparent, with escalating cancer burdens and chronic disease. The challenges to recruitment of minorities in the United States are multiple including trust or lack thereof. Keys to successful recruitment are responding to community issues, its history, beliefs, and its social and economic pressures. The strategy we have used in many low-income, sometimes remote, communities is to recruit staff from the same community and train them in the required basic research methods. They are the first line of communication. After our arrival in the Texas Rio Grande Valley in 2001, we applied these principles learned over years of global research, to studies of chronic diseases. Beginning in 2004, we recruited and trained a team of local women who enrolled in a cohort of over five thousand Mexican Americans from randomly selected households. This cohort is being followed, and the team has remained, acquiring not only advanced skills (ultrasound, FibroScan, retinal photos, measures of cognition, etc.) but capacity to derive key health information. Currently, we are participating in multiple funded studies, including an NIH clinical trial, liver disease, obesity, and diabetes using multiomics aimed at developing precision medicine approaches to chronic disease prevention and treatment.

show abstract