2022
DOI: 10.2147/ijgm.s381160
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Association of Red Blood Cell Distribution Width with Stroke Prognosis Among Patients with Small Artery Occlusion: A Hospital-Based Prospective Follow-Up Study

Abstract: Objective Stroke is the leading cause of mortality and disability worldwide. However, there is no study on the relationship between red blood cell distribution width and the prognosis of small artery occlusion, which is a stroke subtype. This study aimed to assess the association of red blood cell distribution width at admission with outcomes among patients with small artery occlusion. Methods In this hospital-based follow-up study, all included patients were diagnosed … Show more

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Cited by 3 publications
(2 citation statements)
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“…Increased levels of systemic inflammation were correlated with activated circulant platelets, presenting bigger and inequal volumes, resulting in higher MPV (mean platelet volume) and PDW (platelets distribution width) values [ 21 , 22 ]. Similarly, destruction and fragmentation of the erythrocytes in an inflammatory environment, with endothelial activation, sludge, and microcapillary occlusion, was associated with higher RDW (red cell distribution width) values [ 23 ].…”
Section: Introductionmentioning
confidence: 99%
“…Increased levels of systemic inflammation were correlated with activated circulant platelets, presenting bigger and inequal volumes, resulting in higher MPV (mean platelet volume) and PDW (platelets distribution width) values [ 21 , 22 ]. Similarly, destruction and fragmentation of the erythrocytes in an inflammatory environment, with endothelial activation, sludge, and microcapillary occlusion, was associated with higher RDW (red cell distribution width) values [ 23 ].…”
Section: Introductionmentioning
confidence: 99%
“…Excessive oxidative stress reduces the activity of red blood cells ( 23 ). Moreover, elevated RDW levels were found to be associated with the risk of recurrence of small artery occlusion ( 26 ). Pathological changes of cerebral small vessels can cause small artery occlusion and also involve deep ICH.…”
Section: Discussionmentioning
confidence: 99%