Association of Sarcopenia and Body Composition With Postoperative 90-Day Morbidity After Liver Resection for Malignant Tumors

Abstract

and practitioners to identify individuals in urgent need of medical attention. The evidence available indicates that the ODI has excellent psychometric and structural properties, which is not the case for the Maslach Burnout Inventory, the most widely used measure of burnout. 4 Occupational health specialists have persistently come up against the problem of how to define and diagnose burnout, as illustrated again by the findings by Hewitt et al. 1 Somewhat surrealistically, studies claiming to estimate the prevalence of burnout have multiplied despite the absence of a diagnosis. By repatriating the topic of job-related distress in the well-established framework of depression, we have a chance to assess and promote the health of our workforce more effectively.

Effects of sarcopenia and frailty on postoperative recovery in elderly patients: A prospective cohort study

“…A study involving 234 patients after liver resection for malignant tumours reported that patients with sarcopenia had a statistically significantly higher rate of 90‐day morbidity than patients in the other groups and had longer hospital stays and higher readmission rates. 25 Another study involving 404 patients undergoing radical gastrectomy for gastric cancer also found that sarcopenia significantly increased post‐operative morbidity in gastric cancer patients, resulting in longer post‐operative hospital stay and shorter overall survival and disease‐free survival. 26 The reasons for the high morbidity in elderly patients with sarcopenia may be as follows: (1) The decrease of amino acids released by skeletal muscle of sarcopenia patients lead to the lack of raw materials for the synthesis of acute phase proteins by the liver.…”

“…Our study found that sarcopenia was an independent risk factor for post‐operative morbidity, which is consistent with other studies. A study involving 234 patients after liver resection for malignant tumours reported that patients with sarcopenia had a statistically significantly higher rate of 90‐day morbidity than patients in the other groups and had longer hospital stays and higher readmission rates 25 . Another study involving 404 patients undergoing radical gastrectomy for gastric cancer also found that sarcopenia significantly increased post‐operative morbidity in gastric cancer patients, resulting in longer post‐operative hospital stay and shorter overall survival and disease‐free survival 26 .…”

“…For them, operation is a significant physical and psychological blow that drains their limited reserves and leads to decompensation. Several surgical outcome studies focused on groups of high‐risk procedures rather than broadly assessing the risk across diverse surgeries 5,6,15,25 . Our prospective cohort study included multiple types of surgery with different operative stress to explore the impact of sarcopenia and frailty on elderly surgical patients.…”

“…Several surgical outcome studies focused on groups of high‐risk procedures rather than broadly assessing the risk across diverse surgeries. 5 , 6 , 15 , 25 Our prospective cohort study included multiple types of surgery with different operative stress to explore the impact of sarcopenia and frailty on elderly surgical patients. In addition to tracking mortality and complication rates after surgery, we also define ‘recovery’ from the patient's point of view such as 90‐day sleep quality and daily activities.…”

Sarcopenia Imperils Postoperative Long-Term Survival in HCC Patients with Metabolic Dysfunction-Associated Fatty Liver Disease: A Propensity Score Matching Analysis

“… 14 , 15 Especially for patients undergoing surgery, sarcopenia is a common occurrence and has a significant influence on prognosis. Recent studies have indicated that sarcopenia has a negative effect on postoperative outcomes including those for lung cancer, 16 esophageal cancer, 17 liver malignant tumors, 18 and colorectal liver metastases. 19 …”