2022
DOI: 10.1038/s41598-022-19868-0
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Association of serum leptin at 24–28 weeks gestation with initiation and progression of labor in women

Abstract: Concentrations of the hormone leptin, which is produced by adipose tissue, increase with increasing BMI, whereas leptin sensitivity often declines with higher BMI. Thus, altered leptin signaling may play a role in reproductive health risks observed with increasing BMI, which include later onset and slow progression of labor. Conflicting evidence from clinical, animal and in vitro studies have suggested that leptin either promotes or inhibits labor. We hypothesized that serum leptin concentrations or serum lept… Show more

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