Association of Serum Prealbumin with Angiographic Severity in Patients with Acute Coronary Syndrome

Chenglong, Zhang; Liu, Pei; Xia, Ke; Han, Fei; Jiang, Mei; Xie, Qiang-min; Yu, Zaixin; Yang, Tianlun

doi:10.12659/msm.902348

Cited by 24 publications

(21 citation statements)

References 32 publications

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“…12 Liver damage and inflammatory stimulation alter prealbumin levels. 13,15 Several studies of HCC and other types of cancer have suggested that prealbumin may be related to liver function and therefore show prognostic value. Nutritional status closely correlates with postoperative recurrence and prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…These results are consistent with studies of cohorts in China and other countries. 13,15 Several studies of HCC and other types of cancer have suggested that prealbumin may be related to liver function and therefore show prognostic value. One study of patients with HCC found that prealbumin <140 mg/L suggests a dangerously low liver function for patients undergoing hepatectomy, 16 with prealbumin level varying directly with the extent of liver damage.…”

Section: Discussionmentioning

confidence: 99%

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Correlation between serum prealbumin and prognosis of patients with hepatocellular carcinoma after hepatectomy

Jia

Zhong

Huo

et al. 2019

Journal of Surgical Oncology

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Objective To determine whether serum prealbumin levels are associated with long‐term survival after hepatectomy in patients with primary hepatocellular carcinoma(HCC). Methods A consecutive sample of 526 patients with HCC who underwent potentially curative hepatectomy from August 2007 to August 2010 was retrospectively analyzed. Patients were classified as having normal or reduced serum prealbumin based on cut‐off values of 200 or 182 mg/L. Results Multivariate analysis identified the preoperative level of serum prealbumin as an independent prognostic factor of long‐term survival (P < 0.05): Survival was significantly better for those with normal levels than for those with reduced levels, based on either cut‐off value. Similar results were observed in subgroup analyses based on the degree of cirrhosis, level of ɑ‐fetoprotein and Barcelona Clinic Liver Cancer stage. Conclusions Preoperative level of serum prealbumin may be useful for predicting long‐term survival in patients with HCC after hepatectomy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Correlation between serum prealbumin and prognosis of patients with hepatocellular carcinoma after hepatectomy

Jia

Zhong

Huo

et al. 2019

Journal of Surgical Oncology

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“…Decreased levels of PAB could increase free thyroxine, which was associated with adverse outcomes in patients with acute myocardial infarction 31 . Clinical studies have revealed that a lower level of serum PAB was associated with prognosis of heart failure 11–13 , higher overall mortality in critically ill patients 32 , and negatively associated with angiographic severity in patients with ACS 14 . The above research results illustrated that patients with low PAB levels have poor clinical outcomes.…”

Section: Discussionmentioning

confidence: 99%

“…Investigations have shown that PAB in both the acute and chronic heart failure patients could predict mortality 11–13 . A recent study demonstrated that the PAB level is inversely related to angiographic severity score in ACS patients 14 . In our previous study, we found that PAB could independently predict MACE in patients with ACS 15 .…”

Section: Introductionmentioning

confidence: 99%

High sensitivity C-reactive protein to prealbumin ratio measurement as a marker of the prognosis in acute coronary syndrome

Wang

Ren

Wang

et al. 2019

Sci Rep

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The study aimed to determine whether high sensitivity C-reactive protein to prealbumin (hs-CRP/PAB) ratio could be used to predict in-hospital major adverse cardiac events (MACE) in patients with acute coronary syndrome (ACS). A total of 659 patients with ACS were included in the study. Patients were divided into two groups: high hs-CRP/PAB ratio group (hs-CRP/PAB ≥0.010) and low hs-CRP/PAB ratio group (hs-CRP/PAB <0.010). MACE was defined as death, cardiogenic shock, re-infarction and acute heart failure. Logistic regression was performed and the receiver operating characteristic curve (ROC) was generated to evaluate the correlation of hs-CRP/PAB ratio and MACE in patients with ACS. The occurrence rate of MACE was significantly higher in high hs-CRP/PAB ratio group when compared with that in low hs-CRP/PAB ratio group ( P < 0.001). Multivariable analysis determined that hs-CRP/PAB ratio was an independent predictor of MACE (adjusted odds ratio: 1.276, 95% confidence interval: 1.106–1.471, P = 0.001). Moreover, the area under the curve value of hs-CRP/PAB ratio for predicting MACE was higher than hs-CRP and equal to PAB. High hs-CRP/PAB ratio was considered as a prognostic parameter of MACE in ACS patients, with the predictive power equal to PAB but greater than hs-CRP.

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“…Our study also showed that the albumin level was not an independent risk factor for small CAA, but the PA level was an independent risk factor. A possible reason for this result is that PA has a short average lifespan; therefore, it can better estimate the nutritional and inflammatory status of a child at the precise time at which it is measured (35).…”

Section: Discussionmentioning

confidence: 99%

Association between Mycoplasma pneumoniae Infection and Coronary Artery Aneurysm in Children with Kawasaki Disease

et al. 2020

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Background: The epidemiology of Kawasaki disease (KD) suggests that an infectious agent may be a potential disease trigger in susceptible children. Several studies have shown that the cause of KD may be associated with Mycoplasma pneumoniae (M. pneumoniae) infection. Objectives: We aimed to investigate the relationship between M. pneumoniae infection and coronary artery aneurysm (CAA) in children with KD in China. Methods: From January 2015 to December 2018, a total of 330 children with KD met the inclusion criteria. Relevant data were extracted and analysed. Results: The children were stratified into two groups according to M. pneumoniae infection status. Significant differences were identified in the proportion of patients with fever > 10 days, the occurrence of small CAA, and the average serum sodium, pre-albumin (PA), and albumin levels but not in the occurrence of medium and giant CAA between the two groups. According to binary logistic regression, M. pneumoniae infection (OR: 0.515; 95% CI: 0.309 - 0.860; P = 0.011), serum sodium levels (OR: 0.910; 95% CI: 0.851 - 0.972; P =0.005), and PA (OR: 0.900; 95% CI: 0.854 - 0.949; P ≤ 0.001) levels were independently associated with occurrence of small CAA. Conclusions: We demonstrated that M. pneumoniae infection, serum sodium and PA levels are inversely related to the occurrence of small CAA. These results suggest that M. pneumoniae infection may be associated with a decreased incidence of small CAA. Further large-sample studies are needed.

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Association of Serum Prealbumin with Angiographic Severity in Patients with Acute Coronary Syndrome

Cited by 24 publications

References 32 publications

Correlation between serum prealbumin and prognosis of patients with hepatocellular carcinoma after hepatectomy

Correlation between serum prealbumin and prognosis of patients with hepatocellular carcinoma after hepatectomy

High sensitivity C-reactive protein to prealbumin ratio measurement as a marker of the prognosis in acute coronary syndrome

Association between Mycoplasma pneumoniae Infection and Coronary Artery Aneurysm in Children with Kawasaki Disease

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