Association of sexually transmitted infection with semen quality in men from couples with primary and secondary infertility

Bai, Shun; Li, Yuan; Hu, Mei-Hong; Wu, Li; Shui, Lijun; Wang, Xiaohan; Liu, Yi‐Xun; Yue, Qiuling; Yu, Li; Fu, Kaiqiang; Tong, Xianhong; Hu, Xue-Chun; Xu, Bo

doi:10.4103/aja202164

Cited by 8 publications

(2 citation statements)

References 27 publications

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“…C. trachomatis and M. genitalium are caused by a widespread sexually transmitted infection such as infertility ( 12 ). Infections caused by these microorganisms are often asymptomatic.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Chlamydia trachomatis, Ureaplasma parvum and Mycoplasma genitalium in Infertile Couples and the Effect on Semen Parameters

Ahmadi¹,

Moosavian

Mardaneh

et al. 2023

Ethiop J Health Sci

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BACKGROUND: Chlamydia trachomatis, Ureaplasma parvum, and Mycoplasma genitalium are common sexually transmitted microorganisms. Our study aimed to determine the prevalence of C. trachomatis, U. parvum, and M. genitalium in infertile and fertile couples and the effect of these microorganisms on semen parameters. MATERIALS AND METHODS: In this case-control study, samples were collected from 50 infertile couples and 50 fertile couples and were subjected to the routine semen analysis and Polymerase chain reaction (PCR). RESULTS: C. trachomatis and U. parvum were detected in 5 (10%) and 6 (12%) of semen samples from infertile men. Also, out of 50 endocervical swabs from the infertile women, C. trachomatis and M. genitalium were detected in 7(14%) and 4 (8%) of swab specimens, respectively. In the control groups, all of the semen samples and endocervical swabs were negative. Also, in the group of infertile patients infected with C. trachomatis and U. parvum, sperm motility was lower than uninfected infertile men. CONCLUSION: The results of this study showed that C. trachomatis, U. parvum, and M. genitalium are widespread among the infertile couples in Khuzestan Province (Southwest of Iran). Also, our results showed that these infections can decrease the quality of semen. For the prevention of the consequences of these infections, we suggest a screening program for infertile couples.

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“…C. trachomatis and M. genitalium are caused by a widespread sexually transmitted infection such as infertility ( 12 ). Infections caused by these microorganisms are often asymptomatic.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Chlamydia trachomatis, Ureaplasma parvum and Mycoplasma genitalium in Infertile Couples and the Effect on Semen Parameters

Ahmadi¹,

Moosavian

Mardaneh

et al. 2023

Ethiop J Health Sci

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“…(6) It is found in 30-40% of men with primary infertility and 51-77% of men with secondary infertility. (7,8) Varicoceles reduce sperm quantity and quality, it can also effects testicular development in adolescents, cause pain and can decrease testosterone levels. (9) Physical examination is the standard diagnostic method for varicocele, but usually difficult to estimate the existence of varicocele by use of physical examination alone.…”

Section: Introductionmentioning

confidence: 99%

Provocative measures in the sonographic evaluation of varicocele in obese patients and relation of different grades of varicocele with intra-testicular hemodynamics

Hasan,

Gilani,

Hanif

et al. 2024

Preprint

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Background Doppler ultrasonography is typically used to diagnose as a non-invasive imaging technique for the evaluation of varicocele. The Valsalva maneuver and standing position cause reflux of blood through incompetent venous valves, aiding in identifying the varicocele. Varicocele also compromises blood return and leads to an increase in intratesticular artery resistance and pulsatility. However, the efficacy of the standing position Valsalva maneuver and intratesticular artery resistance and pulsatility indices in obese patients for diagnosing varicocele remains uncertain. Obesity presents unique challenges during sonography due to increased adipose tissue and altered venous hemodynamics. Objective To evaluate the effect of standing position and Valsalva maneuver on the sonographic diagnosis of varicocele in obese patients and the relation of different grades of varicocele with intratesticular hemodynamics. Methods This cross-sectional study was conducted at Gilani Ultrasound Centre, Lahore, Pakistan, from March 2019 to October 2023 on 107 obese male patients, and comprised aged 20–45 years diagnosed with varicocele and infertility having varicocele. Patients with testicular surgery, anomalous genitalia, lower limb edema, abdominal ascites or pleural effusion were excluded. Results The mean age of 30.16 ± 3.62 (23 to 39) years. The mean of BMI was 34.51 ± 2.09 (30 to 40), the mean of right-sided varicose veins diameter in laying position was 2.16 ± 0.75 (0.8 to 5.1)mm, while the mean of right-sided varicose veins diameter in standing position was 2.5 ± 0.86 (1.1 to 6.0)mm, and the mean of left-sided varicose veins diameter in laying position was 2.63 ± 0.68 (0.9 to 5.5)mm, while the mean of left-sided varicose veins diameter in standing position was 3.11 ± 0.75 (1.3 to 6.4)mm. The mean of right-sided intratesticular artery resistive index was 0.63 ± 0.07 (0.49 to 0.88), while the mean of left-sided intratesticular artery resistive index was 0.67 ± 0.07 (0.50 to 0.92). Conclusion A significant impact of the provocative measures like standing position and Valsalva maneuver is observed on the sonographic diagnosis of varicocele and statically significant increases in the intratesticular artery resistive and pulsatility indices were noted.

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Effect of leukocytes on semen quality in men from primary and secondary infertile couples: A cross‐sectional study

Fan,

Zhao,

Zhang

et al. 2023

Health Science Reports

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Background and AimsLeukocytospermia (LCS) is a known cause of male infertility. However, the relationship between seminal leukocytes and semen quality among infertile couples remains controversial. This study aims to investigate the association between semen quality and LCS in male partners of infertile couples.MethodsSemen samples were collected from 512 men who asked for a fertility evaluation in a reproductive center in China. Seminal leukocytes were counted following peroxidase staining with benzidine. Other semen parameters were compared in subfertile men with and without LCS.ResultsPoor semen quality (e.g., low semen volume, sperm concentration, and sperm progressive/total motility) was observed among men with LCS compared to those without LCS. Men with LCS had a higher risk of low sperm progressive motility (OR = 0.99, 95% CI = 0.98−0.99, p = 0.02) and total motility (OR = 0.99, 95% CI = 0.98−0.99, p = 0.02), even after adjustment for potential confounders (both OR = 0.99, 95% CI = 0.98−0.99, p = 0.03). Lower sperm viability was observed in LCS from male partners of secondary couples, while no significant difference in semen parameters was found between men with and without LCS in male partners of primary infertile couples. Low sperm motility and viability were associated with LCS in men from secondary infertile couples after adjusting for confounders (OR = 0.97, 95% CI = 0.95−0.99, p = 0.04; OR = 0.94, 95% CI = 0.89−0.99, p = 0.04, respectively).ConclusionsOur findings indicate that a higher risk of abnormal semen parameters was correlated with an increased number of leukocytes in men from secondary infertile couples.

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Association of sexually transmitted infection with semen quality in men from couples with primary and secondary infertility

Cited by 8 publications

References 27 publications

Prevalence of Chlamydia trachomatis, Ureaplasma parvum and Mycoplasma genitalium in Infertile Couples and the Effect on Semen Parameters

Prevalence of Chlamydia trachomatis, Ureaplasma parvum and Mycoplasma genitalium in Infertile Couples and the Effect on Semen Parameters

Provocative measures in the sonographic evaluation of varicocele in obese patients and relation of different grades of varicocele with intra-testicular hemodynamics

Effect of leukocytes on semen quality in men from primary and secondary infertile couples: A cross‐sectional study

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