Association of Smartphone-Based Activity Tracking and Nocturnal Hypoglycemia in People With Type 1 Diabetes

Gardner, Daphne; Tan, Hong Chang; Lim, Gek Hsiang; Zin Oo, May; Xin, Xiaohui; Kingsworth, Andrew; Choudhary, Pratik; Rama Chandran, Suresh

doi:10.1177/19322968231186401

Cited by 1 publication

(2 citation statements)

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“…The total daily dose of insulin used by the participants was 43.9 (14) units per day and 0.66 (0.17) units/kg/day during the study period. There was no relationship between TDD and NH as reported previously 14 . The average Gold score of participants on nights with NH < 3.9 was marginally higher than on nights without NH < 3.9 [2.2(1.1) vs 2.0 (0.9), p = 0.016].…”

Section: Resultssupporting

confidence: 57%

“…All study-related procedures were performed in accordance with the relevant guidelines and regulations. A prior publication from this cohort described the impact of smartphone-based activity tracking on nocturnal hypoglycemia 14 . We excluded those using continuous glucose monitoring and those with an estimated glomerular filtration rate < 30 mL/min/m 2 .…”

Section: Methodsmentioning

confidence: 99%

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Relationship between CGM-derived nocturnal hypoglycemia and subjective sleep quality in people with type 1 diabetes

Gardner,

Tan,

Lim

et al. 2023

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This pilot study explores the relationship between nocturnal hypoglycemia (NH) and subjective sleep quality in people with type 1 diabetes (T1D). Twenty-seven adults with T1D wore a Freestyle Libre Pro CGM and recorded subjective sleep quality daily, as assessed by a single Likert scale question. Frequency, duration, area under the curve (AUC) of NH (00:00–06:00) defined as sensor glucose below threshold (< 3.9 mmol/L; < 3 mmol/L) for ≥ 15 min, nocturnal mean glucose, Time in Range (3.9–10 mmol/L), and coefficient of variation were calculated. Twenty-seven adults, 18 (66.7%) women, with median (IQR) age of 27 (26, 32) years and HbA1c of 7.6 (7.1, 8.1) participated. Nights with NH < 3.9 mmol/L resulted in a lower (worse) sleep score than nights without NH [Mean (SD): 3.3 (1.2) vs 3.5 (1.0), p = 0.03). A higher frequency and longer duration but not AUC [adjusted OR (95% CI) 0.52 (0.38, 0.72), 0.961 (0.932, 0.991), 0.999 (0.998, 1.001) respectively)], of NH < 3.9 mmol/L, were associated with a lower sleep score. NH < 3.0 mmol/L metrics were not associated with sleep quality. Recurrent NH < 3.9 mmol/L, rather than prolonged NH < 3.0 mmol/L, seems associated with subjective sleep quality, implying that those with the highest burden of NH are likely unaware of it.

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Section: Resultssupporting

confidence: 57%

Section: Methodsmentioning

confidence: 99%