Association of Smoking Status With Angina and Health-Related Quality of Life After Acute Myocardial Infarction

Buchanan, Donna M.; Arnold, Suzanne V.; Gosch, Kensey; Jones, Philip G.; Longmore, Lance; Spertus, John A.; Cresci, Sharon

doi:10.1161/circoutcomes.114.001545

Cited by 45 publications

(27 citation statements)

References 47 publications

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“…Critchley et al reviewed 20 studies with 12,603 smoking patients with ischemic heart disease in a meta-analysis and documented that cessation of smoking after acute myocardial infarction or cardiac surgery could significantly reduce mortality [24]. Buchanan et al evaluated the association of smoking status with angina and HRQOL after acute myocardial infarction (AMI) and found that smokers who quitted after AMI had similar angina levels and mental health as non-smokers [25]. In our study, about 42.3% of smokers quitted after DES implantation, who have demonstrated significantly better improvement in HRQOL than persistent smokers and comparable improvement with nonsmokers.…”

Section: Discussionmentioning

confidence: 99%

Impact of smoking on health-related quality of Life after percutaneous coronary intervention treated with drug-eluting stents: a longitudinal observational study

Xue

Bian

Xie

et al. 2017

Health Qual Life Outcomes

101

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BackgroundSmoking has been shown to reduce health-related quality of life (HRQOL) in patients with coronary artery disease (CAD) undergoing percutanous coronary intervention (PCI) either by means of balloon angioplasty or with the use of bare-metal stents (BMS). Drug-eluting stents (DES) have now been widely used and are related to substantial reduction of restenosis and significantly improved HRQOL compared with BMS. This study aimed to evaluate the effects of smoking on HRQOL in patients after PCI in DES era.MethodsA cohort of 649 patients admitted for CAD and treated with drug-eluting stents were included in this prospective, observational study. Patients were classified as non-smokers (n = 351, 54.1%), quitters (n = 126, 19,4%), or persistent smokers (n = 172, 26.5%) according to their smoking status at the time they first admitted to hospital and during the first year of follow-up. Each patient was prospectively interviewed at baseline, 6 months and 1 year following PCI. HRQOL was assessed with the use of Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36).ResultsFor the overall population, HRQOL scores at 1-year follow-up were significantly higher than baseline for all 8 domains. At 1-year follow-up, the HRQOL scores in persistent smokers were still lower than that in non-smokers in 6 domains except for bodily pain and mental health, and than that in quitters in 5 domains except for bodily pain, role emotional and mental health. There were no significant differences with regard to the scores between non-smokers and quitters except role emotional for which non-smokers had higher scores. After adjustment, persistent smokers demonstrated significantly less improvements in HRQOL than non-smokers in 6 domains except for bodily pain and social functioning and significantly less improvement than quitters for general health. Improvements of quitters were comparable to that of non-smokers in all domains. Multivariate linear regression analyses showed persistent smoking was an independent risk factor for PCS and MCS improvements.ConclusionsPersistent smoking substantially diminishes the potential quality-of-life benefits of DES. Efforts should be made to promote smoking cessation after DES implantation which could greatly improve the health quality outcomes.

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Section: Discussionmentioning

confidence: 99%

Impact of smoking on health-related quality of Life after percutaneous coronary intervention treated with drug-eluting stents: a longitudinal observational study

Xue

Bian

Xie

et al. 2017

Health Qual Life Outcomes

101

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“…It is reported that smoking can induce oxidative stress and elevated RDW is correlated with the number of cigarettes smoked per day as well as duration of smoking [ 100 , 101 ]. Smoking has been also proved to be a well-known risk factor in MI [ 102 ]. A study has identified the stronger association between RDW and MI among smokers, which exactly supports the hypothesis that RDW level can reflect the inflammation status [ 24 ].…”

Section: Mechanismsmentioning

confidence: 99%

Red Blood Cell Distribution Width: A Novel Predictive Indicator for Cardiovascular and Cerebrovascular Diseases

2017

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The red blood cell distribution width (RDW) obtained from a standard complete blood count (CBC) is a convenient and inexpensive biochemical parameter representing the variability in size of circulating erythrocytes. Over the past few decades, RDW with mean corpuscular volume (MCV) has been used to identify quite a few hematological system diseases including iron-deficiency anemia and bone marrow dysfunction. In recent years, many clinical studies have proved that the alterations of RDW levels may be associated with the incidence and prognosis in many cardiovascular and cerebrovascular diseases (CVDs). Therefore, early detection and intervention in time of these vascular diseases is critical for delaying their progression. RDW as a new predictive marker and an independent risk factor plays a significant role in assessing the severity and progression of CVDs. However, the mechanisms of the association between RDW and the prognosis of CVDs remain unclear. In this review, we will provide an overview of the representative literatures concerning hypothetical and potential epidemiological associations between RDW and CVDs and discuss the underlying mechanisms.

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“…The DNA amplicons were analyzed on automated pyrosequencing device PSQTMHS96MA (Biotage, Sweden) [10,11] . Primers for pyrosequencing are listed in Table 2 [ [13][14][15][16]20] .…”

Section: Methodsmentioning

confidence: 99%

“…One of the main risk factors for cardiac angina is a atherosclerosis of coronary arteries [2][3][4][5][6] . Other risk factors for cardiac angina include hypertension, diabetes mellitus, obesity, smoking; stress, hypodynamia, infectious diseases, allergic lesions and genetic mutations [7][8][9][10][11][12] .…”

Section: Introductionmentioning

confidence: 99%

Mitochondrial mutations associated with cardiac angina

Рыжкова¹,

Sinyov²,

Sazonova³

et al. 2019

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Aim: Cardiac angina is a disease in which discomfort or retrosternal pain may occur. Atherosclerosis of coronary arteries is one of the main risk factors for cardiac angina. The aim of the investigation was to analyze the association of 11 mitochondrial genome mutations with cardiac angina. In our preliminary studies an association of these mutations with atherosclerosis, a risk factor for cardiac angina, was found. Methods: We used samples of white blood cells collected from 192 patients with cardiac angina and 201 conventionally healthy study participants. DNA from blood leukocyte samples was isolated using a phenol-chloroform method. DNA amplicons containing the investigated regions of 11 mitochondrial genome mutations (m.

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Association of Smoking Status With Angina and Health-Related Quality of Life After Acute Myocardial Infarction

Cited by 45 publications

References 47 publications

Impact of smoking on health-related quality of Life after percutaneous coronary intervention treated with drug-eluting stents: a longitudinal observational study

Impact of smoking on health-related quality of Life after percutaneous coronary intervention treated with drug-eluting stents: a longitudinal observational study

Red Blood Cell Distribution Width: A Novel Predictive Indicator for Cardiovascular and Cerebrovascular Diseases

Mitochondrial mutations associated with cardiac angina

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