Association of Solitary, Segmental Hemangiomas of the Skin With Visceral Hemangiomatosis

Metry, Denise; Hawrot, Aimee; Altman, Carolyn A.; Frieden, Ilona J.

doi:10.1001/archderm.140.5.591

Cited by 120 publications

(90 citation statements)

References 29 publications

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“…[88][89][90][91] Previous retrospective reports 26,81 suggested that the presence of a large or segmental (.5 cm) cutaneous IH might prove a useful marker for hepatic IHs. However, results from a large prospective study suggest that it is the number of cutaneous IHs rather than their size that is the more predictive factor.…”

Section: Highlights Of This Sectionmentioning

confidence: 99%

Diagnosis and Management of Infantile Hemangioma

Darrow¹,

Mancini²,

Nopper³

et al. 2015

Pediatrics

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Infantile hemangiomas (IHs) are the most common tumors of childhood. Unlike other tumors, they have the unique ability to involute after proliferation, often leading primary care providers to assume they will resolve without intervention or consequence. Unfortunately, a subset of IHs rapidly develop complications, resulting in pain, functional impairment, or permanent disfigurement. As a result, the primary clinician has the task of determining which lesions require early consultation with a specialist. Although several recent reviews have been published, this clinical report is the first based on input from individuals representing the many specialties involved in the treatment of IH. Its purpose is to update the pediatric community regarding recent discoveries in IH pathogenesis, treatment, and clinical associations and to provide a basis for clinical decision-making in the management of IH.

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Section: Highlights Of This Sectionmentioning

confidence: 99%

Diagnosis and Management of Infantile Hemangioma

Darrow¹,

Mancini²,

Nopper³

et al. 2015

Pediatrics

Self Cite

215

290

View full text Add to dashboard Cite

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“…Multifocal and diffuse HH correspond with IH, the most common vascular tumor in children that shows a rapid postnatal growth (0-12 mo) followed by slow involution (1-5 years). It is probable that most HH remain undiagnosed since they are asymptomatic self-limiting lesions, although they often come to clinical attention while screening for visceral hemangioma based on the presence of multiple cutaneous IH (Figure 1), since the liver is the most commonly involved organ [3,7,8] . Some patients may develop a congestive heart failure associated with highvolume vascular shunting and treatment is warranted.…”

Section: Hepatic Hemangiomamentioning

confidence: 99%

Differential diagnosis and management of liver tumors in infants

Fernández-Pineda

Cabello-Laureano

2014

WJH

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During the first year of life, most of the liver neoplasms are benign in origin, but some of these histologically benign lesions may be challenging in their management. Although most hepatic hemangiomas can be safely observed until involution is documented, some patients will need treatment due to progressive hepatomegaly, hypothyroidism and/or cardiac failure. Large mesenchymal hamartomas may require extensive hepatic resection and an appropriate surgical plan is critical to obtain good results. For malignant neoplasms such as hepatoblastoma, complete surgical resection is the mainstay of curative therapy. The decision about whether to perform an upfront or delayed resection of a primary liver malignant tumor is based on many considerations, including the ease of resection, surgical expertise, tumor histology and stage, and the likely chemosensitivity of the tumor. This article reviews the initial management of the more common hepatic tumors of infancy, focusing on the differential diagnosis and treatment options.

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“…The importance of diagnosis remains in the fact that there may be associations with intracranial vascular abnormalities, including aneurysm, subarachnoid hemorrhage, anomalous vascular anastomoses, cerebral hypoplasia, hemangiomas and encephalocele 4 . ICA agenesis can be one of the vascular abnormalities constituting the PHACES (posterior fossa malformations, hemangiomas, arterial malformations, coarctation of the aorta/ cardiac defects, eye abnormalities and sternal defects) syndrome 9 , and there also are reports on its associations with neurofibromatosis types I and II 10,11 . Congenital Horner's syndrome is rarely described in association with ICA agenesis 7,12,13 .…”

Section: Discussionmentioning

confidence: 99%

The missed missing hole

Porto

Silva

Domingues

et al. 2012

Arq. Neuro-Psiquiatr.

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In everyday clinical practice, neurologists frequently encounter complex clinical cases in which a full analysis of several variants are essential to reach the right diagnosis. The resolution of a doubtful case may rely on the recognition of a very specific diagnostic clue. The objective of this report was to describe a case in which the prompt recognition of a very subtle imaging feature in the emergency room could have precluded further extensive diagnostic investigations. case rePorTA 34-year-old woman came into the Emergency department with a worsening headache. The symptoms had begun two weeks earlier, with a holocranial pulsatile headache that gradually worsened and became unbearable in the preceding three days. In association with the pain, she complained of nausea, vomiting and intolerance to movement, light and sound. As relevant medical history, she had dyslipidemia and was taking anphepramona for obesity. She had suffered occasional headaches in the past, but never of that intensity. She had already used several over the counter analgesics and nonsteroidal anti-inflammatory drugs with no relief.Neurologic examination disclosed left eye ptosis, which she claimed to be preexisting (Fig A), confirmed on an old photograph. Cerebrospinal fluid analysis was normal. A magnetic resonance angiogram (MRA) of the internal carotid artery (ICA) demonstrated no signal within left ICA (Fig B) absTracT At times in clinical neurology, the identification of a subtle clinical or radiological sign can lead to prompt diagnosis of a very rare or difficult case. We report on a patient who presented with untreatable headache and unilateral ptosis. Computed tomography (CT) scan of the head did not reveal any structural cause. Magnetic resonance angiogram showed absence of left internal carotid artery, which was eventually confirmed by a catheter angiography. Reviewing the case, it emerged that a feature on the initial CT scan "bone window" would have confirmed the diagnosis, had it been searched for: the underdeveloped carotid canal, which is a consequence and a marker of internal carotid artery agenesis.Key words: carotid artery agenesis, Horner syndrome, carotid canal underdevelopment, computed tomography. resumo Em algumas circunstâncias, o reconhecimento de um sinal clínico ou radiológico sutil pode tornar simples o diagnóstico de um caso raro ou muito difícil em neurologia clínica. Relatamos o caso de uma paciente que apresentava cefaleia intratável e ptose palpebral unilateral. A tomografia computadorizada (TC) de crânio não permitiu identificar nenhuma causa estrutural. A ressonância magnética evidenciou ausência da artéria carótida interna esquerda, posteriormente confirmada por arteriografia convencional. Retrospectivamente, descobriu-se que um dado da janela óssea da primeira TC de crânio teria confirmado o diagnóstico, tivesse ele sido pesquisado: o hipodesenvolvimento do canal carotídeo, que é uma consequência e um marcador de agenesia da artéria carótida interna.Palavras-Chave: agenesia da artéria carótida, sínd...

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Association of Solitary, Segmental Hemangiomas of the Skin With Visceral Hemangiomatosis

Cited by 120 publications

References 29 publications

Diagnosis and Management of Infantile Hemangioma

Diagnosis and Management of Infantile Hemangioma

Differential diagnosis and management of liver tumors in infants

The missed missing hole

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