“…Erythema multiforme is a clinically distinct syndrome of multiple aetiology affecting the skin and mucous membranes, and rarely the kidneys (Comaish and Kerr, 1961), producing lesions with some histological similarities to acute nephritis, although the normal blood-pressure, transient arthralgia, and occult blood in the stools may suggest anaphylactoid purpura syndrome. Drugs, sera, streptococci, viruses, mycoplasma pneumoniae (Ludlam et al, 1964), and chemical substances (Yaffee and Stargardter, 1963) have been blamed-as they have in all the necrotizing "allergic" angiitides (Winkelmann and Ditto, 1964). It is possible to link nephritis and erythema multiforme in Case 1, imputing as an antigen the foreign material from the insect bites or the fish.…”