Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality

Liu, Dan; Huang, Qingmei; Song, Weiqi; Li, Zhihao; Chen, Mao

doi:10.7326/l22-0369

Cited by 3 publications

(1 citation statement)

References 2 publications

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“…Tea consumption was then categorized into five groups: >0 to 1.5 cups/day, >1.5 to 2.5 cups/day, >2.5 to 3.5 cups/day, >3.5 to 4.5 cups/day, and >4.5 cups/day, which were equivalent to an average of 1, 2, 3, 4, and 5 or more cups/day, respectively. 23 The association between tea consumption categories (five groups) with incident VTE with no tea consumption as the reference group was further examined among participants adding different additives (no additives, only milk, only sweeteners, and both milk and sweeteners). Models included the adjustments for age, sex (female, male), ethnicity (white, black, Asian, others), assessment centers, BMI, education levels, TDI, smoking status (never, previous, current), alcohol consumption (daily or almost daily, 1–4 times a week, 1–3 times a month, never or special occasions only), healthy diet scores, physical activity, hypertension, diabetes, hypercholesterolemia, and use of aspirin.…”

Section: Methodsmentioning

confidence: 99%

Tea Consumption, Milk or Sweeteners Addition, Genetic Variation in Caffeine Metabolism, and Incident Venous Thromboembolism

Xiang,

Liu,

Zhou

et al. 2024

Thromb Haemost

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Objective The association between tea consumption and venous thromboembolism (VTE) remains unknown. We aimed to evaluate the association between tea consumption with different additives (milk and/or sweeteners) and incident VTE, and the modifying effects of genetic variation in caffeine metabolism on the association. Methods A total of 190,189 participants with complete dietary information and free of VTE at baseline in the UK Biobank were included. The primary outcome was incident VTE, including incident deep vein thrombosis and pulmonary embolism. Results During a median follow-up of 12.1 years, 4,485 (2.4%) participants developed incident VTE. Compared with non-tea drinkers, tea drinkers who added neither milk nor sweeteners (hazard ratio [HR]: 0.85; 95% confidence interval [95% CI]: 0.76–0.94), only milk (HR: 0.86; 95% CI: 0.80–0.93), and both milk and sweeteners to their tea (HR: 0.90; 95% CI: 0.81–0.99) had a lower risk of VTE, while those who added only sweeteners to their tea did not (HR: 0.94; 95% CI: 0.75–1.17). Moreover, there was an L-shaped relationship between tea consumption and incident VTE among tea drinkers who added neither milk nor sweeteners, only milk, and both milk and sweeteners to their tea, respectively. However, a nonsignificant association was found among tea drinkers who added only sweeteners to their tea. Genetic variation in caffeine metabolism did not significantly modify the association (p-interaction = 0.659). Conclusion Drinking unsweetened tea, with or without added milk, was associated with a lower risk of VTE. However, there was no significant association between drinking tea with sweeteners and incident VTE.

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Section: Methodsmentioning

confidence: 99%

Tea Consumption, Milk or Sweeteners Addition, Genetic Variation in Caffeine Metabolism, and Incident Venous Thromboembolism

Xiang,

Liu,

Zhou

et al. 2024

Thromb Haemost

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Replacing traditional coffee appraisers with inductively coupled plasma - mass spectrometry (ICP-MS): From manual sensory evaluation to scientific analysis

Pan,

Yan,

et al. 2024

Food Chemistry: X

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Association of milk consumption with all-cause mortality and cardiovascular outcomes: a UK Biobank based large population cohort study

Zhou

Lin

et al. 2023

J Transl Med

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Background The association of milk consumption with mortality and cardiovascular disease (CVD) outcomes was unclear. Objective The present study was performed to reveal the association of full cream, semi-skimmed, skimmed, soy, and other milk with all-cause mortality and CVD outcomes. Methods A prospective cohort study was performed using data from the UK Biobank. This study recruited 450,507 participants without CVD at baseline between 2006 and 2010 from UK Biobank and followed them up through 2021. Cox proportional hazard models were adopted to calculate the hazard ratios (HRs) and 95% confidence interval (CI) to understand the correlation between milk consumption and clinical outcomes. Subgroup and sensitivity analyses were further conducted. Results Among the participants, 435,486 (96.7%) were milk consumers. Multivariable model indicated that the adjusted HR of association between milk consumption and all-cause mortality was 0.84 (95% CI 0.79 to 0.91; P = 0.000) for semi-skimmed milk; 0.82 (0.76 to 0.88; P = 0.000) for skimmed milk and 0.83 (0.75 to 0.93; P = 0.001) for soy milk. Semi-skimmed, skimmed, and soy milk use were significantly related to lower risks of CVD mortality, CVD event, and stroke. Conclusion Compared with non-milk users, semi-skimmed milk, skimmed milk, and soy milk consumption were related to a lower risk of all-cause mortality and CVD outcomes. Among them, skim milk consumption was more beneficial for all-cause mortality, while soy milk consumption was more beneficial for CVD outcomes.

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Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality

Cited by 3 publications

References 2 publications

Tea Consumption, Milk or Sweeteners Addition, Genetic Variation in Caffeine Metabolism, and Incident Venous Thromboembolism

Tea Consumption, Milk or Sweeteners Addition, Genetic Variation in Caffeine Metabolism, and Incident Venous Thromboembolism

Replacing traditional coffee appraisers with inductively coupled plasma - mass spectrometry (ICP-MS): From manual sensory evaluation to scientific analysis

Association of milk consumption with all-cause mortality and cardiovascular outcomes: a UK Biobank based large population cohort study

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