2020
DOI: 10.1016/j.jiph.2019.07.004
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Association of the infectious triggers with childhood Henoch–Schonlein purpura in Anhui province, China

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Cited by 46 publications
(46 citation statements)
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“…IgA vasculitis (Henoch-Schönlein purpura) is a small-vessel vasculitis mediated by immune-complexes deposits containing IgA. It is usually preceded by respiratory tract infections and its association with multiple microorganisms is known, including different viruses 8 . The main clinical manifestations are nonthrombocytopenic purpura, arthritis/arthralgia, and abdominal pain 8,9,S1,S2 .…”
Section: Discussionmentioning
confidence: 99%
“…IgA vasculitis (Henoch-Schönlein purpura) is a small-vessel vasculitis mediated by immune-complexes deposits containing IgA. It is usually preceded by respiratory tract infections and its association with multiple microorganisms is known, including different viruses 8 . The main clinical manifestations are nonthrombocytopenic purpura, arthritis/arthralgia, and abdominal pain 8,9,S1,S2 .…”
Section: Discussionmentioning
confidence: 99%
“…Infections may be one of the several possible triggers participating in the pathogenesis; the most common infectious trigger detected was streptococcal infections. 2 Although there are a few reports of EBV infection in children with HSP, 3 to our knowledge, this is the first report of EBV-associated haemorrhagic bullous HSP. Deposition of IgA or C3 in skin biopsy materials is diagnostic for HSP.…”
mentioning
confidence: 79%
“…The purpura are often palpable, erythematous and of varying sizes. Skin biopsy and subsequent histopathological analysis demonstrate areas of leukocytoclastic vasculitis, and immunofluorescence shows IgA deposition in vessel walls [4][5][6].…”
Section: Introductionmentioning
confidence: 99%
“…There have been several cases of HSP presenting with antecedent immunological insult, such as a bacterial or viral infection. One study by Albaramki showed that 41.9% of patients with HSP presented with a preceding upper respiratory tract infection [1,4]. Incidents of purpura following infection with streptococcus, Epstein-Barr virus (EBV) and varicella have also been documented.…”
Section: Introductionmentioning
confidence: 99%