Association of the spectral features of heart period signal with SNP of NOS in the Chinese Han nationality population

Abstract

To explore association of the spectral features of heart period signal with SNPs at 5 sites of NOS gene in the subjects (male89, female77, aged 62.40+/-2.5 yrs) by allele specific primer PCR technique. It was found that the TT allelic genotype of NOS2 C-1173T associated with the highest RPH and TT allelic genotype of NOS3 G894T associated with the highest APH in HPS spectral parameters. This suggests the SNPs of NOS2 C-1173T and NOS3 G894T may be the deep layer factors to result in the variability of HPS spectral parameters.