Association of Timing of Plasma Transfusion With Adverse Maternal Outcomes in Women With Persistent Postpartum Hemorrhage

Henriquez, Dacia D. C. A.; Caram‐Deelder, Camila; Cessie, Saskia le; Zwart, Joost J.; Roosmalen, J.J.M. van; Eikenboom, Jeroen; So‐Osman, Cynthia; Watering, Leo M.G. van de; Zwaginga, Jaap Jan; Gemert, A.W.M.M. Koopman-van; Bloemenkamp, Kitty W. M.; Bom, Johanna G. van der

doi:10.1001/jamanetworkopen.2019.15628

Cited by 25 publications

(23 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is unclear whether early FFP transfusion leads to improved maternal outcomes. In an observational study of 1216 women with persistent PPH (defined as ≥1000 mL blood loss refractory to first‐line intervention), FFP transfused within 60 minutes of persistent PPH onset was not associated with reduced severe hemorrhage‐related morbidity (defined as a composite of death, hysterectomy, or arterial embolization) compared with no or later FFP transfusion . In a different observational study, the restrictive use of FFP in 605 women with a moderate to severe PPH and a FIBTEM A5 greater than 15 mm did not result in ongoing bleeding secondary to hemostatic failure .…”

Section: Key Approaches To Managing Active Bleeding In Patients With mentioning

confidence: 96%

How do I manage severe postpartum hemorrhage?

2020

View full text Add to dashboard Cite

show abstract

Section: Key Approaches To Managing Active Bleeding In Patients With mentioning

confidence: 96%

How do I manage severe postpartum hemorrhage?

2020

View full text Add to dashboard Cite

show abstract

“…However, current data do not support any one method for quantifying blood loss as superior to another (10) . A study performed in the Netherlands in women with persistent postpartum hemorrhage found that early fresh frozen plasma transfusion (within the first 60 minutes) was not associated with maternal deaths, hysterectomies, or arterial embolizations, compared with no or later plasma transfusion (11) . In addition, nearly one quarter of all maternal deaths in the United States from 2013 to 2016 were related to sepsis, and over one third of those deaths occurred after hospital discharge (12) .…”

Section: Detrimental Health Effects During Pregnancymentioning

confidence: 99%

Del Editor sobre la Salud de la Mujer, Posibles efectos perjudiciales sobre la salud en el embarazo y la menopausia

Romero

2020

Rev peru ginecol obstet.

View full text Add to dashboard Cite

La esperanza de vida al nacer en todos los países está por encima de la paridad diagonal línea: en todo el mundo, una niña recién nacida puede esperar vivir más que un niño recién nacido (1). Debido a esto, se debe implementar la atención médica preventiva desde el nacimiento. Además, durante el período reproductivo, los ginecólogos debe aconsejar a las futuras madres que gocen de buena salud cuando quedar embarazada y evitar embarazos no deseados o forzados y posibles amenazas ambientales para el feto. Un grupo de investigadores tiene descubrió que las partículas de carbono negro se acumulan en el lado fetal del placenta; Esto sugiere que las partículas ambientales podrían ser transportadas hacia el feto (2). Mujeres embarazadas que están expuestas a la atmósfera. los niveles de contaminación durante su segundo embarazo pueden estar en mayor riesgo de parto prematuro, en comparación con su primer embarazo (3).

show abstract

“…In recent years, though for PPH treatment work has made great progress, refractory PPH was still lack of effective solutions 4–6 . In clinical practice, some cases of amniotic fluid embolism causing death could be caused by refractory PPH as reported 7–9 . Affected by the lack of medical emergency equipment, the death rates of PPH were even higher in developing countries and poor countries 10–12 …”

Section: Introductionmentioning

confidence: 99%

Circular suture of the uterine serosa and myometrium layer around placental attachment site for refractory postpartum hemorrhage

Shi

Liu

et al. 2021

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Objective The aim of the study was to analyze the clinical outcomes of circular suture at placental attachment site for refractory postpartum hemorrhage (PPH), which could block blood supply of the serosa and myometrium layer. Methods Eighty cases of refractory PPH were enrolled and retrospective analyzed in this study for further analysis from a consecutive single center database between 2010 and 2018. After undergoing circular suture of the uterine serosa and myometrium layer around placental attachment site, surgical and perioperative outcomes were recorded and analyzed. Results Among all the patients enrolled, 28 cases (35.0%) of refractory PPH were mainly caused by uterine inertia, 36 cases (45.0%) caused by ectopic placenta, and 2 cases (2.5%) caused by coagulation disorders. After circular suture of the uterine serosa and myometrium layer at placental attachment site, all the uterine active bleeding was controlled below 40 ml without recurrence. The perioperative results were similar between the vaginal and cesarean sections groups. Conclusions Circular suture of the uterine serosa and myometrium at the placental attachment site could control refractory PPH with few postoperative complications. Circular suture around placenta site could be applied in time to protect the endometrium even in primary hospital.

show abstract

Association of Timing of Plasma Transfusion With Adverse Maternal Outcomes in Women With Persistent Postpartum Hemorrhage

Abstract: This cohort study examines the association of timing of receipt of plasma transfusions among women experiencing persistent postpartum hemorrhage with adverse maternal outcomes.

Cited by 25 publications

References 65 publications

How do I manage severe postpartum hemorrhage?

How do I manage severe postpartum hemorrhage?

Del Editor sobre la Salud de la Mujer, Posibles efectos perjudiciales sobre la salud en el embarazo y la menopausia

Circular suture of the uterine serosa and myometrium layer around placental attachment site for refractory postpartum hemorrhage

Contact Info

Product

Resources

About