2023
DOI: 10.1136/bmjopen-2022-069807
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Association of trajectories of non-high-density lipoprotein cholesterol concentration with risk of cardiovascular disease: the Kailuan Study

Abstract: ObjectivesThis study aimed to assess the association between longitudinal change in non-high-density lipoprotein cholesterol (non-HDL-C) and subsequent cardiovascular disease (CVD) risk.DesignA retrospective study.SettingData were obtained from the Kailuan Study, a dynamic cohort study initiated in 2006 in Tangshan, China.ParticipantsThe current study included 41 085 participants (mean age 53.9±11.6 years) free of CVD events in or before 2012. The non-HDL-C trajectory was developed according to the repeated me… Show more

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