Association of visceral and subcutaneous fat with glucose intolerance, insulin resistance, adipocytokines and inflammatory markers in Asian Indians (CURES-113)

Indulekha, Karunakaran; Anjana, R M; Surendar, Jayagopi; Mohan, Viswanathan

doi:10.1016/j.clinbiochem.2010.12.015

Cited by 96 publications

(89 citation statements)

References 36 publications

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“…Leptin has been proposed to be involved in energy homeostasis and modulation of insulin sensitivity [62] also being positively associated with visceral adipose mass [63]. Recent studies have revealed that serum levels of leptin are inversely associated with serum 25(OH)D which is in agreement with our results.…”

Section: Vitamin D and Dysfunctional Adipose Tissuesupporting

confidence: 83%

Influence of Vitamin D Deficiency on Cardiometabolic Risk in Obesity

Stokić¹,

Hakkak²,

Romani³

et al. 2017

J Obes Chronic Dis

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Section: Vitamin D and Dysfunctional Adipose Tissuesupporting

confidence: 83%

Influence of Vitamin D Deficiency on Cardiometabolic Risk in Obesity

Stokić¹,

Hakkak²,

Romani³

et al. 2017

J Obes Chronic Dis

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“…For SAT, this relation is considerably attenuated or nonexistent [68][69][70][71][72]. Adiponectin levels are negatively correlated to both VAT and SAT [69,[72][73][74][75], although the correlation with VAT is consistently stronger than the correlation with SAT [69,72,74].…”

Section: Quantitative Measurement Of Visceral Adipose Tissue (Vat) Anmentioning

confidence: 82%

Untitled

2016

Horm Metab Res

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“…The level of CRP and IL-6 reported is approximately 10-fold higher than what we have observed in our study population. 26 It has been reported in German populations that serum adiponectin, hsCRP, and IL-6 levels were not significantly different between IFG and IGT individuals 30 but no information is available from other ethnic groups.…”

Section: Discussionmentioning

confidence: 99%

“…A recent study done by Mohan et al indicated profiling of serum adiponectin in healthy, IGT, and diabetic individuals. 26 Adiponectin levels in IFG individuals were not evaluated in that study.…”

Section: Discussionmentioning

confidence: 99%

Adiponectin and IL-6

et al. 2013

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These authors contributed equally to this work. Keywords: inflammation, adipokines, prediabetic, biomarkerAim: The objective of the study was to identify the association if any, of inflammatory markers (adiponectin and IL-6) with fasting glucose in normoglycemic (healthy), prediabetic (impaired fasting glucose), and hyperglycemic (diabetic) people in Indian population.Methods: Total 162 volunteers were distributed into 3 groups (normoglycemic, individuals with impaired fasting glucose, and hyperglycemic) as per aDa criterion. The blood chemistry parameters were analyzed and serum adiponectin and IL-6 levels were measured by eLIsa.Results: significant reduction was observed in serum adiponectin level in hyperglycemic and impaired fasting glucose population compared with normoglycemic population. significant reduction in adiponectin was also observed in impaired fasting glucose group compared with hyperglycemic group. similarly significant increase was also observed in IL-6 level in hyperglycemic and impaired fasting glucose groups compared with normoglycemic group.Conclusions: From our data it can be summarized that there is a significant change in both adiponectin (reduction) and IL-6 (increase) levels in normoglycemic (healthy), prediabetic (impaired fasting glucose), and hyperglycemic (diabetic) population in Indian population. There is a significant but gradual change during the progression of healthy toward diabetic population via pre-diabetic condition.

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Association of visceral and subcutaneous fat with glucose intolerance, insulin resistance, adipocytokines and inflammatory markers in Asian Indians (CURES-113)

Cited by 96 publications

References 36 publications

Influence of Vitamin D Deficiency on Cardiometabolic Risk in Obesity

Influence of Vitamin D Deficiency on Cardiometabolic Risk in Obesity

Untitled

Adiponectin and IL-6

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