Objectives: To evaluate associations among Lipid Profile, Mucin1 CETP status between adult normal control subjects (NCs) and cholelithiasis i.e. gallstone disease (GSD) patients (Pts) preoperatively (I 0 ) and postoperatively (II 0 ) with laparoscopic cholecystectomy. Patients and Methods: Adult Pts with GSD (N=55, Gender: 10 males, 45 females; Age range: 28-60 years, Mean age ± SD: 45.5±12.2 years) and NCs (N: 40, Gender: 16 males, 24 females, Mean age + SD: 42.5+10.5 Years) were those reported in our previous case-control prospective interventional studies carried out from October 2016 to March 2018 at MRU, MHWT, Uttara, Dhaka, Bangladesh. Serum lipid profile (TG, TC, LDL-C, HDL-C), Lp(a), ApoA1, ApoB100, ApoE, Mucin1 and CETP status in NCs (I 0 ) and Pts (I 0 , II 0 ) were reported in the recent past. Further advanced statistical analyses on these data were made according to the objectives of the present article as stated above regarding associations (correlations) among these staus by using SPSS programme-version 26. Results: About associations among the Lipid Profile and Mucin1 status between NCs (I 0 ) and Pts (I 0 , II 0 ), significant Pearson correlations were found for Pts-TG (Serum-I 0 ) vs Pts-TG (Serum-II 0 ) (r=0.545, p=0.001), Pts-TC (Serum-I 0 ) vs Pts-TC (Serum-II 0 ) (r=0.385, p=0.025) and Pts-LDL-C (Serum-I 0 ) vs Pts-LDL-C (Serum-II 0 ) (r=0.393, p=0.022). No significant associations (correlations) were obtained for HDL-C among the groups compared (p>0.05). Although significant association (correlation) was obtained for Pts-Mucin1 (Serum-I 0 ) vs Pts-Mucin1 (Serum-II 0 ) (r=0.766, p=0.000), no significant associations (correlations) were found for TG vs Mucin1 status and TC vs Mucin1 status for any of the groups compared (p>0.05). However, significant associations were shown for Pts LDL-C (Serum-I 0 ) vs Pts Mucin1 (Serum-II 0 ) (r=0.381, p=0.026), Pts-HDL-C (Serum-I 0 ) vs Pts-Mucin1 (Serum-II 0 ) (r=0.475, p=0.005) and NCs-HDL-C (Serum-I 0 ) vs Pts-Mucin1 (Bile-I 0 ) (r=0.419, p=0.026) respectively. Regarding associations for Abu S. M. Giasuddin et al.