Associations between an international COVID-19 job exposure matrix and SARS-CoV-2 infection among 2 million workers in Denmark

Abstract

OBJECTIVES: This study investigates the associations between the Danish version of a job exposure matrix for COVID-19 (COVID-19-JEM) and Danish register-based SARS-CoV-2 infection information across three waves of the pandemic. The COVID-19-JEM consists of four dimensions on transmission: two on mitigation measures, and two on precarious work characteristics. METHODS: The study comprised 2 021 309 persons from the Danish working population between 26 February 2020 and 15 December 2021. Logistic regression models were applied to assess the associations between the JEM dimensions and overall score and SARS-CoV-2 infection across three infection waves, with peaks in March–April 2020, December–January 2021, and February–March 2022. Sex, age, household income, country of birth, wave, residential region and during wave 3 vaccination status were accounted for. RESULTS: Higher risk scores within the transmission and mitigation dimensions and the overall JEM score resulted in higher odds ratios (OR) of a SARS-CoV-2 infection. OR attenuated across the three waves with ranges of 1.08–5.09 in wave 1, 1.06–1.60 in wave 2, and 1.05–1.45 in those not (fully) vaccinated in wave 3. In wave 3, no associations were found for those fully vaccinated. In all waves, the two precarious work dimensions showed weaker or inversed associations. CONCLUSIONS: The COVID-19-JEM is a promising tool for assessing occupational exposure to SARS-CoV-2 and other airborne infectious agents that mainly spread between people who are in close contact with each other. However, its usefulness depends on applied restrictions and the vaccination status in the population of interest.

Potential Work-related Exposure to SARS-CoV-2 by Standard Occupational Grouping Based on Pre-lockdown Working Conditions in France

“…COVID-19-JEM, for example, is the result of an iterative process involving experts from three countries (Denmark, the Netherlands, and the UK) to categorize occupations according to eight workplace factors believed to be associated with COVID-19: four determinants of risk of transmission; number of contacts; nature of contacts (co-workers, general public, or patients with COVID-19); contaminated workspaces and location (indoors or outdoors); two mitigation measures; social distancing and face covering; and two precarious work factors; income insecurity and proportion of migrants [ 6 ]. This JEM has been validated by comparing risk scores assigned by the COVID-19-JEM with self-reported data among the Dutch workers [ 7 ] and by estimating the associations between the COVID-19-JEM risk scores and COVID-19 in the UK [ 8 ], Denmark [ 9 ], and the Netherlands [ 7 ].…”