Associations Between Bacterial Vaginosis and Urgency Urinary Incontinence in Women: An Analysis of Nhanes 2001 to 2004

Xie, Li; Yu, Zhuoyuan; Gao, Fei

doi:10.1016/j.urology.2022.07.053

Cited by 4 publications

(2 citation statements)

References 23 publications

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“…Additionally, research has shown that BV may be associated with urinary incontinence, and women with BV were more likely to report SUI [ 35 ]. BV is characterized by a decrease in Lactobacillus (the dominant species in a healthy vaginal microbiota) and an increase in anaerobic bacteria such as Gardnerella , Prevotella , and Atopobium , leading to pelvic floor disorders (PFD) [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of stress urinary incontinence on vaginal microbial communities

Zhang,

Zhou,

Yao

et al. 2024

BMC Microbiol

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Background Postpartum women often experience stress urinary incontinence (SUI) and vaginal microbial dysbiosis, which seriously affect women’s physical and mental health. Understanding the relationship between SUI and vaginal microbiota composition may help to prevent vaginal diseases, but research on the potential association between these conditions is limited. Results This study employed 16S rRNA gene sequencing to explore the association between SUI and vaginal dysbiosis. In terms of the vaginal microbiota, both species richness and evenness were significantly higher in the SUI group. Additionally, the results of NMDS and species composition indicated that there were differences in the composition of the vaginal microbiota between the two groups. Specifically, compared to postpartum women without SUI (Non-SUI), the relative abundance of bacteria associated with bacterial dysbiosis, such as Streptococcus, Prevotella, Dialister, and Veillonella, showed an increase, while the relative abundance of Lactobacillus decreased in SUI patients. Furthermore, the vaginal microbial co-occurrence network of SUI patients displayed higher connectivity, complexity, and clustering. Conclusion The study highlights the role of Lactobacillus in maintaining vaginal microbial homeostasis. It found a correlation between SUI and vaginal microbiota, indicating an increased risk of vaginal dysbiosis. The findings could enhance our understanding of the relationship between SUI and vaginal dysbiosis in postpartum women, providing valuable insights for preventing bacterial vaginal diseases and improving women’s health.

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Section: Discussionmentioning

confidence: 99%

Effect of stress urinary incontinence on vaginal microbial communities

Zhang,

Zhou,

Yao

et al. 2024

BMC Microbiol

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“…Previous studies have shown that pregnancy can lead to changes in the composition of vaginal microbiota in women [26]. Additionally, research has shown that BV is positively linked to the emergence of SUI and that women who have bacterial vaginosis are more likely to report experiencing SUI [27]. BV is characterized by a decrease in Lactobacillius (the dominant species in a healthy vaginal microbiota) and an increase in anaerobic bacteria such as Gardnerella, Prevotella, and Atopobium, leading to pelvic oor disorders (PFD) [28].…”

Section: Discussionmentioning

confidence: 99%

Effect of Stress Urinary Incontinence on Vaginal Microbiota Stability

Zhang,

Zhou,

Yao

et al. 2023

Preprint

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Background Stress urinary incontinence and vaginal microbial dysbiosis frequently occur in postpartum women. A better understanding of the relationship between SUI and the composition of vaginal microbiota may help to prevent the emergence of vaginal diseases. However, limited research has been conducted to investigate the potential association between vaginal microbial dysbiosis and stress urinary incontinence. Results The present study revealed a strong correlation between changes in the composition of vaginal microbiota and stress urinary incontinence, with stress urinary incontinence being more likely to lead to dysbiosis of vaginal microbiota. In terms of the vaginal microbiota, both alpha diversity and evenness were significantly higher in the stress urinary incontinence group compared to the group without stress urinary incontinence. Additionally, there were notable differences in the composition of the vaginal microbiota between two groups. Specifically, among stress urinary incontinence patients, the abundance of bacteria associated with bacterial vaginosis, such as Streptococcus, Prevotella, Dialister, and Veillonella, showed an increase, while the abundance of Lactobacillus decreased. Furthermore, the vaginal microbial co-occurrence network of stress urinary incontinence patients displayed higher connectivity, complexity, and clustering. Conclusions As a result, our study emphasizes the significant role of Lactobacillus in maintaining homeostasis within the vaginal microbial community. A correlation between stress urinary incontinence and the vaginal microbiota was observed, indicating an increased risk of vaginal microbial disorders and bacterial vaginosis for individuals with stress urinary incontinence. Consequently, we anticipate that our findings will contribute novel insights into the prevention of bacterial vaginal diseases associated with stress urinary incontinence.

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