Associations between depressive symptoms, anxiety symptoms, their comorbidity and health-related quality of life: a large-scale cross-sectional study

Liao, Wei; Luo, Zhicheng; Dong, Xiaokang; Wu, Xinyuan; Mei, Yongxia; Cui, Ningning; Kang, Ning; Lan, Yali; Liu, Xiaotian; Huo, Wenqian; Wang, Fang; Wang, Chongjian

doi:10.1186/s12889-021-11969-1

Cited by 14 publications

(8 citation statements)

References 44 publications

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“…In the current study, QoL was significantly related to depression and anxiety disorders in both rural and urban residents. Similar findings were reported by Liao et al (2021), who studied almost 24,000 rural residents in China, where both depressive symptoms and anxiety disorders significantly decreased QoL and affected both men and women [52]. Kang et al (2021) presented results confirming that comorbid chronic diseases and unhealthy lifestyle negatively influence QoL.…”

Section: Discussionsupporting

confidence: 85%

“…Women living in urban areas rated their QoL significantly lower than men (p <0.005), but in the case of rural residents, the differences in the assessment of QoL between men and women were not so significant. Nevertheless, Liao et al (2021) found that women in rural populations had lower QoL. They also described a relationship between depressive symptoms and reduced QoL.…”

Section: Discussionmentioning

confidence: 96%

“…They also described a relationship between depressive symptoms and reduced QoL. These authors explained this by the fact that people with depressive and anxiety symptoms showed fatigue and loss of energy, feelings of slowness or agitation and anxiety, poor attention and concentration, impaired memory, and indecisiveness, which could ultimately lead to a low QoL [52].…”

Section: Discussionmentioning

confidence: 99%

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Sleep problems and related factors in rural and urban populations in Western Pomerania, Poland

Wolińska¹,

Mroczek²

2022

Ann Agric Environ Med.

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Introduction.Insomnia is considered the most common sleep disorder. Sleep deprivation, regardless of its causes, leads to deterioration in the quality of life (QoL), poorer daytime functioning, and reduced professional productivity. It also contributes to an increase in the number of occupational and road accidents. Most research on sleep problems has been conducted on samples of urban residents, with few studies among people living in rural areas, where high rates of sleep problems have also been recorded.Objective. The aim of the study was to determine sleep problems and their impact on the QoL of rural and urban residents of the West Pomeranian Province of Poland. Materials and method. The study involved 597 people: 187 (31.32%) rural and 410 (68.68%) urban residents. The research instruments used in the study were standardized questionnaires, namely the Athens Insomnia Scale (AIS), Insomnia Severity Index (ISI), Epworth Sleepiness Scale (ESS), and the Short Form 36 Health Survey (SF-36), and the author's questionnaire concerning socio-demographic data.Results. There was a statistically significant relationship between insomnia and gender, both among rural (p < 0.050) and urban (p < 0.005) residents. Diseases that turned out to be significantly related to insomnia in rural residents were diabetes (p < 0.045) and depression (p < 0.015). Women living in the city assessed their QoL worse than men (p < 0.0005). The lowest QoL was demonstrated in people with insomnia. Conclusions: The results suggest that insomnia is often a permanent condition in the Polish population. Bearing in mind the prevalence of insomnia among Poles, especially in the 60-79 age group, it is necessary to introduce obligatory tests of sleep disorders and QoL into the practice of a family doctor, due to the long-term adverse effects of persistent insomnia.

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

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Sleep problems and related factors in rural and urban populations in Western Pomerania, Poland

Wolińska¹,

Mroczek²

2022

Ann Agric Environ Med.

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“…We also found that anxiety played a role in the decreased EQ‐5D‐5L index values in MSA and lower EQ VAS scores of MSA‐P (Du et al., 2018). Depression and anxiety were associated with a lower EQ‐5D‐5L index value and EQ VAS score in the Chinese elderly (Liao et al., 2021). A previous study found that more severe depressive symptoms were determinants of lower EQ VAS scores in MSA and progressive supranuclear palsy (Winter et al., 2011).…”

Section: Discussionmentioning

confidence: 99%

Health‐related quality of life in patients with multiple system atrophy using the EQ‐5D‐5L

et al. 2022

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Background Multiple system atrophy (MSA) is an incurable neurodegenerative disease. We aimed to investigate the health‐related quality of life (HRQoL) and the determinants of HRQoL in patients with MSA. Methods The five‐level EuroQol five‐dimensional questionnaire (EQ‐5D‐5L) was used to evaluate patients’ HRQoL. The results of HRQoL were indicated by the EQ‐5D‐5L index values and visual analog scale (EQ VAS) scores. Specific scales were used to measure disease severity, cognition, frontal lobe function, anxiety, depression, fatigue, and sleep disorders. The beta mixture model and the linear regression model were used to explore the determinants of HRQoL in patients with MSA. Results A total of 205 patients with cerebellar variants (MSA‐C; 53.9%) and 175 patients with parkinsonian variants (MSA‐P; 46.1%) were included in this cross‐sectional study. The mean values of the EQ‐5D‐5L index values and EQ VAS scores were .558 and 59.5, respectively. Problem with mobility was the problem reported by the highest proportion of patients (92.1%), followed by problems with usual activities (88.7%), self‐care (81.3%), anxiety/depression (72.1%), and pain/discomfort (53.9%). The determinants of the lower EQ‐5D‐5L index values in patients with MSA were greater disease severity, fatigue, Parkinson's disease‐related sleep problems (PD‐SP), depressive mood, and anxious mood. Greater disease severity, fatigue, and depressive mood were associated with lower EQ VAS scores. Conclusion The problem reported most frequently by Chinese individuals with MSA was mobility. In addition to the greater disease severity of MSA, fatigue, PD‐SP, depression, and anxiety were determinants of poor HRQoL.

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“…In addition, analysis of variance (ANOVA) and Student t test were performed to test the differences in continuous variables. Based on the Chinese value set for the EQ-5D-5L, different domains and different levels had different coefficients (MO = 0.345, SC = 0.253, UA = 0.233, PD = 0.302, AD = 0.258, L 1 = 0, L 2 = 0.191, L 3 = 0.458, L 4 = 0.832, and L 5 = 1), and the utility value calculation formula was as follows: utility = 1 − MO × Ln − SC × Ln − UA × Ln − PD × Ln − AD × Ln ( n = 1, 2, 3, 4, 5) [ 23 ]. The ceiling effect was calculated as the proportion of patients who reported no problems in all dimensions [ 24 ].…”

Section: Methodsmentioning

confidence: 99%

Health-Related Quality of Life and Utility Scores of Posttreatment Patients with Gastric Cancer at Different Pathological Stages: A Cross-Sectional Study

Zhang

Sun

Chen

et al. 2022

Journal of Oncology

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Background. Health-related quality of life (HRQoL) is a key variable in the evaluation of health economics. We aimed to evaluate the HRQoL and utility scores of patients with gastric cancer and related precancerous lesions by assessing their quality of life using a single standardized health measurement instrument. Methods. A cross-sectional study was conducted in six counties in Shangdong Province from November 2019 to March 2020. Subjects with precancerous lesions and gastric cancer (cardia and noncardia) were included and surveyed. Patients were divided into four groups: low-grade intraepithelial neoplasia (LGIN), high-grade intraepithelial neoplasia (HGIN), early gastric cancer (EGC), and advanced gastric cancer (AGC). All patients, except those with LGIN, received treatment. The five-level EQ-5D was used to assess HRQoL and generate utility scores using the Chinese-specific tariff published in 2017. Results. The study included 566 respondents. The average utility was 0.927 for precancerous lesions (LGIN: 0.930; HGIN: 0.926), 0.906 for early gastric cancer (EGC), and 0.756 for advanced gastric cancer (AGC). Visual analogue scale (VAS) means were 76.82 (LGIN: 78.08; HGIN: 74.81), 72.26, and 69.16 for precancerous lesions, EGC, and AGC, respectively. HRQoL was lower in women with AGC than in men (0.612 vs. 0.792, P = 0.035 ). AGC patients were more likely to report problems across all five dimensions than patients in other stages. The proportion of patients reporting pain/discomfort problems was highest across all gastric cancer stages (LGIN, 35.6%; HGIN, 34.4%; EGC, 35.6%; and AGC, 55.7%), followed by anxiety/depression (LGIN, 17.5%; HGIN, 18%; EGC, 22.8%; and AGC, 47.7%). Conclusions. HRQoL declined as cancer progressed, with the most dramatic decline observed in patients with AGC. A more advanced pathological stage was associated with a greater decrease in health utility. The obtained utilities for different pathological stages of gastric cancer were significant parameters for researchers to perform further cost-utility analysis. Pain/discomfort and anxiety/depression were problems that seriously affected the patients in all groups.

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Associations between depressive symptoms, anxiety symptoms, their comorbidity and health-related quality of life: a large-scale cross-sectional study

Cited by 14 publications

References 44 publications

Sleep problems and related factors in rural and urban populations in Western Pomerania, Poland

Sleep problems and related factors in rural and urban populations in Western Pomerania, Poland

Health‐related quality of life in patients with multiple system atrophy using the EQ‐5D‐5L

Health-Related Quality of Life and Utility Scores of Posttreatment Patients with Gastric Cancer at Different Pathological Stages: A Cross-Sectional Study

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