Associations between peripheral vertigo and gastroesophageal reflux disease

Viliušytė, Edita; Macaitytė, Raminta; Vaitkus, Antanas; Rastenytė, Daiva

doi:10.1016/j.mehy.2015.06.007

Cited by 9 publications

(2 citation statements)

References 24 publications

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“…Studies also revealed an association between LPR and halitosis, taste, or smelling disorders [44,45]. Researchers have recently reported that acid reflux may be associated with middle and inner ear problems, such as otitis media, tinnitus, and peripheral vertigo [46][47][48]. The mechanism underlying these inner ear disorders may be associated with reflux material (specifically hydrochloric acid and pepsin) leaking into the middle ear via the Eustachian tubes and affecting osseous structures.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

Laryngopharyngeal Reflux: An Update

Kuo¹

2019

AOHNS

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Laryngopharyngeal reflux (LPR), also referred to as extra-esophageal reflux, supra-esophageal reflux, or silent reflux, refers to a condition in which gastroduodenal content rises up the esophagus and affects the throat, specifically the laryngopharynx [1-6]. In some cases, gastric content may even reach the nasal cavities and/or ears via the Eustachian tubes, which can exacerbate rhinitis, sinusitis, or otitis media [7-9]. Otolaryngologists and gastroenterologists differ in their definitions and management of LPR [4,10-12]. Otolaryngologists treat LPR as a relatively new clinical entity, whereas gastroenterologists treat LPR as a rare extra-esophageal manifestation of gastroesophageal reflux disease (GERD) [10,13]. Gastroenterologists have questioned whether reflux contributes to LPR-related symptoms in patients with no GERD-associated manifestations [11]. Otolaryngologists have pointed out that LPR is a multifactorial syndrome that also involves gaseous and/or nonacid refluxate [14,15]. In this article, we examine the clinical manifestations, diagnosis, and current recommended treatments of LPR. Based on the latest findings in LPR research, we propose an algorithm aimed at facilitating the assessment and management of LPR. Differences Between LPR and GERD Despite similarities between LPR and GERD, these are two distinct disease entities. The retrograde flow of gastroduodenal contents into the esophagus and/or adjacent structures can lead to complications or troublesome reflux-associated symptoms, such as throat clearing, heartburn, and globus pharyngeus. Reflux diseases can be categorized as LPR, erosive esophagitis, and nonerosive reflux disease (NERD). Cases of erosive esophagitis and NERD are categorized as GERD [16]. In GERD, the reflux of gastric contents is limited to the esophagus. In LPR, the reflux of gastric content affects the larynx and pharynx [12]. Despite occasional cross-diagnoses of GERD and LPR, there are essential differences (Table 1). GERD is accompanied by acidity and heartburn (retrosternal burning), which is rarely encountered in LPR patients [12]. In GERD, reflux and acidity typically occur during the night (nocturnal refluxers). In LPR, reflux typically occurs during the day (daytime refluxers) [12]. LPR symptoms occur when patients are in an upright position during periods of physical exertion (e.g., bending over, Valsalva, and exercise) [11,12,17], whereas GERD reflux occurs while patients are lying down.

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Section: Clinical Manifestationsmentioning

confidence: 99%

Laryngopharyngeal Reflux: An Update

Kuo¹

2019

AOHNS

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“…Consequently, the individual's professional and social life is seriously affected by vertigo, and therefore, there is a tendency to use complementary and alternative therapies (15). Moreover, in conventional medicine, the concept of relationship between peripheral vertigo and gastrointestinal reflux disease has been mentioned and some potential mechanisms are proposed (16), this type of vertigo, is well discussed in Traditional Persian Medicine (TPM) textbooks and named as gastric related vertigo (GRV) which has simple and low-cost treatments with minimal side effects (17)(18)(19)(20)(21)(22)(23)(24). Vertigo is widely studied by TPM scholars and is known as "Dowar".…”

Section: Introductionmentioning

confidence: 99%

Reliability and validity of a questionnaire for diagnosis of clinical gastric related vertigo: A Traditional Persian Medicine perspective and prevalence assessment

Monfared¹,

Karimi-Yazdi²,

Hashem-Dabaghian³

et al. 2019

Electron. physician

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Background: Chronic vertigo is a frustrating and expensive disease affecting individuals and society. Scientists of Traditional Persian Medicine (TPM) have a long held belief that there is a common type of vertigo originated from the stomach known as gastric related vertigo (GRV) and there are present, simple and low-cost treatments for GRV based on its categorization. Objective: To develop a valid tool for assessing GRV and determining the prevalence of this type of vertigo. Methods: In this cross-sectional study, a questionnaire was designed based on GRV indices. To determine the intra-rater reliability, a test-retest method was used and kappa coefficient was measured by Statistical Package for the Social Sciences software (SPSS, version 17). Content validity ratio (CVR) and content validity index (CVI) for each question were calculated by using Lawshe table. The reliable version of the questionnaire was assessed in a sample of 135 patients with a chronic true vertigo which lasts more than three months and aged between 18 and 65 years. This study was conducted in the outpatient clinics of several university hospitals in Tehran, Iran, between May 2016 and November 2017. Results: A valid 30-item questionnaire with CVR more than 0.62, CVI more than 0.78 and kappa coefficient more than 0.7 was the main achievement of this study, which can be useful for assessment of GRV in future clinical trials. The study showed that 98 participants (72.59%) had at least one criterion of GRV. Conclusion: According to the high prevalence of GRV among patients who suffer from chronic vertigo, more studies in this field including clinical trial are suggested.

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Commentary on “Clinical and audiologic characteristics of patients with sensorineural tinnitus and its association with psychological aspects: an analytic retrospective study”

Lou

2017

Eur Arch Otorhinolaryngol

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Associations between peripheral vertigo and gastroesophageal reflux disease

Cited by 9 publications

References 24 publications

Laryngopharyngeal Reflux: An Update

Laryngopharyngeal Reflux: An Update

Reliability and validity of a questionnaire for diagnosis of clinical gastric related vertigo: A Traditional Persian Medicine perspective and prevalence assessment

Commentary on “Clinical and audiologic characteristics of patients with sensorineural tinnitus and its association with psychological aspects: an analytic retrospective study”

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