Associations between personality traits and adherence to treatment in patients with primary open–angle glaucoma in an African population

Abu, Emmanuel Kwasi; Antiri, Ebenezer Oduro; Ocansey, Stephen; Ntodie, Michael; Abokyi, Samuel; Abraham, Carl Halladay

doi:10.1080/08164622.2022.2075253

Cited by 4 publications

(1 citation statement)

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“…For instance, Adachi et al (2022) reported a significant positive correlation between conscientiousness and medication adherence in patients with cardiovascular diseases, with no significant relationship observed with other personality traits. Similarly, Abu et al (2023) found that both conscientiousness and agreeableness could significantly predict medication adherence, while neuroticism, extraversion, and openness to experience demonstrated no significant association.…”

Section: Introductionmentioning

confidence: 93%

Intertemporal decision-making as a mediator between personality traits and self-management in type 2 diabetes: a cross-sectional study

et al. 2023

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ObjectivesThe aims to investigate the mediating effect of intertemporal decision-making on the association between personality traits and self-management among individuals with in Type 2 Diabetes (T2DM).MethodPatients with T2DM in the early stages of hospitalization at two tertiary hospitals in Shenyang and Jinzhou, Liaoning Province, May 2022 to January 2023. Questionnaires, including General Demographic, Self-Management, Big Five Personality, and Intertemporal Decision-Making, were administered. Pearson correlation analysis examined relationships between personality traits, intertemporal decision-making, and self-management. Hierarchical regression analysis identified self-management predictors. Mediation analysis used the PROCESS SPSS Macro version 3.3 model 4 to investigate intertemporal decision-making as mediator between personality traits and self-management.ResultsPearson correlation analysis revealed significant associations between self-management scores, personality traits, and intertemporal decision-making. Hierarchical regression revealed that Neuroticism and Conscientiousness accounted for 20.8% of the variance in self-management, while intertemporal decision-making explained 4.5% of the variance. Finally, using the Bootstrap method, the mediation analysis showed that intertemporal decision-making partially mediated the effect of personality traits on self-management.ConclusionThis study emphasizes the importance of intertemporal decision-making in improving self-management behaviors among patients with T2DM. Interventions targeted at modifying intertemporal decision-making preferences could be effective in enhancing self-management behaviors, leading to better health outcomes.

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Section: Introductionmentioning

confidence: 93%

Intertemporal decision-making as a mediator between personality traits and self-management in type 2 diabetes: a cross-sectional study

et al. 2023

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Personality traits and other factors associated with psychotropic medication non-adherence at two hospitals in Uganda. A cross-sectional study

Niyokwizera,

Nitunga,

Muhumuza

et al. 2024

PLoS ONE

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Mental illnesses, like other chronic illnesses, require medications for both immediate, short term and long-term treatment. Medication adherence is the first and most important factor for better treatment outcomes. Non-adherence to psychotropic medications is associated with relapse, readmission, and early death. Psychological factors are among the common factors associated with non-adherence. Specific personality traits moderate the beliefs about medication that influence non-adherence to medications. Sociodemographic and clinical factors can also influence non-adherence to psychotropic medications. Non-adherence to psychotropic medications is high in Africa. Still, to the best of our knowledge, there is a lack of studies on the level of psychotropic medication non-adherence and associated personality traits. The aim was to determine the prevalence of psychotropic medication non-adherence and associated personality traits among people with mental illness attending Kampala International University Teaching Hospital (KIU-TH) and Jinja Regional Referral Hospital (JRRH). This study employed a hospital-based cross-sectional design. 396 adult patients suffering from mental illness were collected from KIU-TH and JRRH outpatient clinics. Medication adherence was assessed using the Medication Adherence Rating Scale (MARS) while personality traits were assessed by the short form of the Big Five Inventory (Ten Items Personality Inventory). In our study, we first assessed sociodemographic and clinical factors influencing psychotropic medication non-adherence (confounders). A questionnaire with sociodemographic information was also used. Logistic regression was used to assess personality traits and other factors associated with psychotropic medication non-adherence. The majority of the study participants were males (59.1%), from rural areas (74.2%), with a secondary educational level (47.5%) and unemployed (44.9%). The prevalence of psychotropic medication was 46.21%. Poor family support (aOR = 6.915, CI = 3.679–12.998, P<0.001), belief in witchcraft/sorcery (aOR = 2.959, CI = 1.488–5.884, P = 0.002), experiencing side effects (aOR = 2.257, CI = 1.326–3.843, P = 0.003), and substance use (aOR = 4.174, CI = 2.121–8.214, P<0.001) were factors significantly associated with psychotropic medication non-adherence. The personality traits significantly associated with psychotropic medication non-adherence after controlling for the confounders were neuroticism (aOR = 7.424, CI = 3.890–14.168, P<0.001) and agreeableness (aOR = 0.062, CI = 0.024–0.160, P<0.001). In this study, medication non-adherence was high. Non-adherent patients were more likely to have predominant neuroticism personality traits. Non-adherence to medication was shown to be less common in individuals with agreeableness personality traits. Other factors associated with psychotropic medication non-adherence were poor social support, witchcraft beliefs, the presence of side effects, and substance use. Specific interventions should be done for patients with a high risk of being non-adherent to psychotropic medications, with the involvement of all stakeholders including caregivers, parents, tutors, and trustees.

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The self-medication behaviors of residents and the factors related to the consideration of drug efficacy and safety—A cross-sectional study in China

Zhang²,

Zhang³

et al. 2023

Front. Pharmacol.

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Background: Over-the-counter (OTC) drugs facilitates residents self-medication. However, inappropriate self-medications have become a serious problem in China and even all over the world.Objectives: To make an investigation on the current status of Chinese residents’ self-medication behaviors and important considerations, and to explore the factors related to the considerations of drug efficacy and safety.Design: A quantitative, cross-sectional study.Methods: Multi-stage sampling was used to conduct a cross-sectional investigation in China 22 provinces, 5 autonomous regions and 4 municipalities directly under the Central Government. State that an interviewer-administrated questionnaire, was used for data collection. The questionnaire that was used in the investigation included demographic sociological characteristics, health literacy scale-short form (HLS-SF), the 10-item Big Five Inventory (BFI-10), the EuroQol-5D visual analogue scale (EQ-5D VAS), self-medication status and important considerations when self-medicating. Descriptive statistics were performed, and the Chi-square test was used for univariate analysis. Log-binomial regression was used for multivariate analysis on whether residents regard drug efficacy or safety as an important consideration.Results: 9256 respondents were included in the data analysis. The self-medication rate of Chinese adults was as high as 99.1%. Paracetamol and other analgesics were the most common types of OTC medication that respondents purchased, followed by vitamins/minerals. Medical staff recommendations, drug safety and efficacy were the top three important considerations. The residents in the east, central and western regions who consider safety is 63.5%, 61.5%, and 66.8% respectively. The proportion of curative effect was 60.2%, 55.7%, and 61.4% respectively. Log-binomial regression showed that western respondents, retired people, those who mainly used ways including basic medical insurance for employees, commercial medical insurance, free medical treatment to cover their medical cost, respondents with high neuroticism, high health literacy were more likely to consider drug safety as an important factor (p < 0.05). Eastern respondents, employed, main way of medical expenses borne was Out-of-pocket Payment, those with chronic disease were more likely to consider drug efficacy as an important factor (p < 0.05). Female, respondents with high levels of agreeableness, conscientiousness, openness, and self-rated health status were more likely to regard both drug safety and efficacy as important considerations (p < 0.05).Conclusion: Self-medication is practiced by most Chinese adults. Whether Chinese adults take drug efficacy or safety as an important consideration is related to their demographic and sociological characteristics, Big Five personality characteristics, health literacy and self-assessed health status. There is a need to strengthen the management of OTC drugs and public education about self-medication.

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Associations between personality traits and adherence to treatment in patients with primary open–angle glaucoma in an African population

Cited by 4 publications

References 43 publications

Intertemporal decision-making as a mediator between personality traits and self-management in type 2 diabetes: a cross-sectional study

Intertemporal decision-making as a mediator between personality traits and self-management in type 2 diabetes: a cross-sectional study

Personality traits and other factors associated with psychotropic medication non-adherence at two hospitals in Uganda. A cross-sectional study

The self-medication behaviors of residents and the factors related to the consideration of drug efficacy and safety—A cross-sectional study in China

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