Associations between psychedelic use, abuse, and dependence and lifetime panic attack history in a representative sample

Bonn‐Miller, Marcel O.; Bernstein, Amit; Sachs‐Ericsson, Natalie; Schmidt, Norman B.; Zvolensky, Michael J.

doi:10.1016/j.janxdis.2006.09.014

Cited by 14 publications

(15 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A population study reported that any lifetime use of cocaine and/or psychedelics was associated with prior lifetime history of two or more of 15 psychotic symptoms, but not one psychotic symptom [39]; in this study cocaine and amphetamine use were not included as control variables in the analyzes of psychedelic use, although both cocaine and amphetamine use were reported to be associated with psychotic symptoms; although the data came from a 10-year longitudinal study, data were aggregated over all time periods and no distinction was made between psychotic symptoms occurring before or after onset of psychedelic use. Another retrospective population study did not find an association between any lifetime “psychedelic” use and panic attacks or depression, but did report an association between dependence on “psychedelics” and panic attacks [40]; however, in this study the number of events was small, and the dissociative anesthetic PCP was included as a psychedelic, even though it is well known that PCP has quite different subjective effects, dependence potential, and neurobiological mechanisms than the serotonergic psychedelics. A follow-up of 29 patients with first-break psychosis attributed to LSD use found that these individuals were “essentially similar” to first-break psychosis patients with no LSD use in terms of premorbid adjustment, course of illness, and family history of inpatient treatment, and course of illness [41] (see also [28]).…”

Section: Discussionmentioning

confidence: 62%

Psychedelics and Mental Health: A Population Study

2013

View full text Add to dashboard Cite

BackgroundThe classical serotonergic psychedelics LSD, psilocybin, mescaline are not known to cause brain damage and are regarded as non-addictive. Clinical studies do not suggest that psychedelics cause long-term mental health problems. Psychedelics have been used in the Americas for thousands of years. Over 30 million people currently living in the US have used LSD, psilocybin, or mescaline.ObjectiveTo evaluate the association between the lifetime use of psychedelics and current mental health in the adult population.MethodData drawn from years 2001 to 2004 of the National Survey on Drug Use and Health consisted of 130,152 respondents, randomly selected to be representative of the adult population in the United States. Standardized screening measures for past year mental health included serious psychological distress (K6 scale), mental health treatment (inpatient, outpatient, medication, needed but did not receive), symptoms of eight psychiatric disorders (panic disorder, major depressive episode, mania, social phobia, general anxiety disorder, agoraphobia, posttraumatic stress disorder, and non-affective psychosis), and seven specific symptoms of non-affective psychosis. We calculated weighted odds ratios by multivariate logistic regression controlling for a range of sociodemographic variables, use of illicit drugs, risk taking behavior, and exposure to traumatic events.Results21,967 respondents (13.4% weighted) reported lifetime psychedelic use. There were no significant associations between lifetime use of any psychedelics, lifetime use of specific psychedelics (LSD, psilocybin, mescaline, peyote), or past year use of LSD and increased rate of any of the mental health outcomes. Rather, in several cases psychedelic use was associated with lower rate of mental health problems.ConclusionWe did not find use of psychedelics to be an independent risk factor for mental health problems.

show abstract

Section: Discussionmentioning

confidence: 62%

Psychedelics and Mental Health: A Population Study

2013

View full text Add to dashboard Cite

show abstract

“…In a state-wide cross-sectional sample of adults in Colorado, a lifetime history of PAs was associated with an increased rate of lifetime alcohol dependence (but not alcohol abuse or use, [60] and with psychedelic abuse and dependence (but not psychedelic use) [61] Goodwin et al [44] found significant cross-sectional associations with alcohol dependence and nicotine dependence. Another cross-sectional study looking at a wider range of substances (opioids, sedatives, cocaine, and amphetamines) found that lifetime and past year PAs were associated with past year substance use disorders (as well as anxiety and depressive disorders), after controlling for neuroticism, gender, and co-existing anxiety disorders.…”

Section: Comorbiditymentioning

confidence: 96%

“…[44] There are several possible explanations such as some individuals with PAs using substances to reduce their anxiety. [62] Alternatively, Bonn-Miller et al [61] proposed that use of substances, especially psychedelic drugs, may increase the risk for future PAs due to repetitive exposure to interoceptive processes associated with the substance. Finally, there may be a third variable such as a common genetic link or personality [63] between PAs and substance use disorders.…”

Section: Comorbiditymentioning

confidence: 99%

Panic disorder: a review of DSM-IV panic disorder and proposals for DSM-V

et al. 2010

View full text Add to dashboard Cite

This review covers the literature since the publication of DSM-IV on the diagnostic criteria for panic attacks (PAs) and panic disorder (PD). Specific recommendations are made based on the evidence available. In particular, slight changes are proposed for the wording of the diagnostic criteria for PAs to ease the differentiation between panic and surrounding anxiety; simplification and clarification of the operationalization of types of PAs (expected vs. unexpected) is proposed; and consideration is given to the value of PAs as a specifier for all DSM diagnoses and to the cultural validity of certain symptom profiles. In addition, slight changes are proposed for the wording of the diagnostic criteria to increase clarity and parsimony of the criteria. Finally, based on the available evidence, no changes are proposed with regard to the developmental expression of PAs or PD. This review presents a number of options and preliminary recommendations to be considered for DSM-V.

show abstract

“…Together smokers with PD are characterized by a problematic set of beliefs and behaviors that likely impede their ability to successfully refrain from smoking. However, little research has examined malleable affective vulnerabilities that may indirectly play a role in the relation between PD and smoking cognitions (Piper, Cook, Schlam, Jorenby, & Baker, 2011; Zvolensky et al, 2004). …”

Section: Introductionmentioning

confidence: 99%

The indirect effect of panic disorder on smoking cognitions via difficulties in emotion regulation

Yang

Zvolensky

Leyro

2017

Addictive Behaviors

Self Cite

View full text Add to dashboard Cite

Panic disorder (PD) and cigarette smoking are highly comorbid and associated with worse panic and smoking outcomes. Smoking may become an overlearned automatized response to relieve panic-like withdrawal distress, leading to corresponding smoking cognitions, which contribute to its reinforcing properties and difficultly abstaining. Difficulties in emotion regulation (ER) may underlie this relation such that in the absence of adaptive emotion regulatory strategies, smokers with PD may more readily rely upon smoking to manage affective distress. In the current study, the indirect relation between PD status and smoking cognitions through ER difficulties was examined among daily smokers (N=74). We found evidence for an indirect relation between PD status and negative affect, addictive and habitual smoking motives, and anticipating smoking will result in negative reinforcement and personal harm, through self-reported difficulties with ER. Our findings are aligned with theoretical models on anxiety and smoking, and suggest that reports of greater smoking cognitions may be due to ER difficulties.

show abstract

Associations between psychedelic use, abuse, and dependence and lifetime panic attack history in a representative sample

Cited by 14 publications

References 29 publications

Psychedelics and Mental Health: A Population Study

Psychedelics and Mental Health: A Population Study

Panic disorder: a review of DSM-IV panic disorder and proposals for DSM-V

The indirect effect of panic disorder on smoking cognitions via difficulties in emotion regulation

Contact Info

Product

Resources

About