Objective
Our aim was to study potential impact of neighbourhood socio-economic status (SES) on all-cause mortality in atrial fibrillation (AF) patients treated in primary care.
Methods
Study population includes adults (n=12,283) of 45 years and older diagnosed with AF in 75 primary care centres in Sweden. Association between neighbourhood SES and all-cause mortality was explored using Cox regression analysis, with hazard ratios (HRs) and 95% confidence intervals (95% CIs); and by Laplace regression where years to death (95% CI) of the first 10% of the participants were used as an outcome. All models were conducted in both men and women and adjusted for age, educational level, marital status, change of neighborhood status, cardiovascular co-morbidities, anticoagulant treatment and statin treatment. High- and low- neighbourhood SES were compared with middle SES as reference group.
Results
After adjustments for potential confounders, higher relative risk of all-cause mortality (HR 1.49, 95% CI 1.13-1.96) was observed in men living in low SES neighborhoods compared to those from middle SES neighbourhoods. The results were confirmed using Laplace regression; the time until the first 10% of the men in low SES neighbourhoods died was 1.45 (95% CI 0.48-2.42) years shorter than for the men in middle SES neighbourhoods.
Conclusions
Increased rates of heart disease and subsequent mortality among adults in deprived neighbourhoods raises important clinical and public health concerns. These findings could serve as an aid to policy-makers when allocating resources in primary health care settings as well as to clinicians who encounter patients in deprived neighbourhoods.